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右冠状动脉口血栓形成伴发心肌梗死和系统性栓塞:一例报告

Concomitant myocardial infarction and systemic embolism associated with thrombosis of the right coronary ostium: a case report.

作者信息

Fuchs Flávio Danni, Amon André Barcellos, Borges Aníbal Pires, Fuchs Felipe Costa, Gonçalves Sandro Cadaval

机构信息

Division of Cardiology, Graduate Program in Cardiology, School of Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2350, Porto Alegre, RS 90035-903, Brazil.

出版信息

Eur Heart J Case Rep. 2024 Nov 15;8(12):ytae605. doi: 10.1093/ehjcr/ytae605. eCollection 2024 Dec.

DOI:10.1093/ehjcr/ytae605
PMID:39659456
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11630029/
Abstract

BACKGROUND

Sequential occurrences of acute ischaemic stroke in patients with acute myocardial infarction (MI) and vice versa have been reported, but not the simultaneous occurrence of both conditions. We report a case of simultaneous occurrence of MI and systemic embolism caused by a mechanism not reported to date.

CASE SUMMARY

A 52-year-old female patient presented with concurrent chest pain, right arm weakness, and dysphasia. An electrocardiogram demonstrated ST-elevation MI. A computed tomography angiography ruled out aortic dissection and showed an ischaemic stroke and infarction in the right kidney and spleen. A right coronary thrombotic occlusion at the ostium was successfully recanalized. Transoesophageal echocardiography showed preserved left ventricular function with no intracardiac thrombi.

DISCUSSION

The reported case presentation does not align with the mechanisms typically associated with simultaneous MI and stroke. The most plausible hypothesis is that the thrombus in the right coronary ostium extended into the aorta, resulting in a concurrent systemic embolism.

摘要

背景

已有报道称急性心肌梗死(MI)患者会相继发生急性缺血性卒中,反之亦然,但两种情况同时发生的情况尚未见报道。我们报告一例由迄今未报道的机制导致的MI和系统性栓塞同时发生的病例。

病例摘要

一名52岁女性患者同时出现胸痛、右臂无力和言语困难。心电图显示ST段抬高型心肌梗死。计算机断层血管造影排除了主动脉夹层,并显示右肾和脾脏有缺血性卒中和梗死。右冠状动脉开口处的血栓性闭塞成功再通。经食管超声心动图显示左心室功能正常,无心腔内血栓。

讨论

报道的病例表现与通常与MI和卒中同时发生相关的机制不符。最合理的假设是右冠状动脉开口处的血栓延伸至主动脉,导致同时发生系统性栓塞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d90/11630029/3cdfcb3cd486/ytae605f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d90/11630029/9107ef5c865b/ytae605il2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d90/11630029/3cdfcb3cd486/ytae605f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d90/11630029/9107ef5c865b/ytae605il2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d90/11630029/3cdfcb3cd486/ytae605f1.jpg

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本文引用的文献

1
Concurrent acute myocardial infarction and acute ischemic stroke: Case reports and literature review.并发急性心肌梗死和急性缺血性卒中:病例报告及文献综述
Front Cardiovasc Med. 2022 Nov 1;9:1012345. doi: 10.3389/fcvm.2022.1012345. eCollection 2022.
2
Nonbacterial Thrombotic Endocarditis with Multiple Systemic Emboli in a Patient with Primary Lung Cancer.原发性肺癌患者合并多系统栓塞的非细菌性血栓性心内膜炎
J Cardiovasc Echogr. 2022 Apr-Jun;32(2):129-131. doi: 10.4103/jcecho.jcecho_68_21. Epub 2022 Aug 17.
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Temporal Trends, Predictors, and Outcomes of Acute Ischemic Stroke in Acute Myocardial Infarction in the United States.
美国急性心肌梗死中急性缺血性脑卒中的时间趋势、预测因素和结局。
J Am Heart Assoc. 2021 Jan 19;10(2):e017693. doi: 10.1161/JAHA.120.017693. Epub 2021 Jan 5.
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Incidence and Outcomes of Myocardial Infarction in Patients Admitted With Acute Ischemic Stroke.急性缺血性卒中患者入院时心肌梗死的发生率及转归
Stroke. 2017 Nov;48(11):2931-2938. doi: 10.1161/STROKEAHA.117.018408. Epub 2017 Oct 10.