Coleman Craig I, Donovan Fariba, Miriyapalli Lahar, Shan Ryan, Lovelace Belinda
School of Pharmacy, University of Connecticut, Storrs, Connecticut, USA.
Valley Fever Center for Excellence, University of Arizona College of Medicine-Tucson, Tucson, Arizona, USA.
Open Forum Infect Dis. 2024 Nov 27;11(12):ofae706. doi: 10.1093/ofid/ofae706. eCollection 2024 Dec.
Coccidioidal meningitis (CM) requires lifelong aggressive management, often necessitating hospitalization. In the National Inpatient Sample (2019-2021), CM hospitalizations (N = 2305) were associated with frequent CM-related procedures (63.6% [95% confidence interval {CI}, 59.3%-67.6%]), long stays (mean, 13.0 days [95% CI, 11.3-14.6 days]), substantial costs per stay (mean, $48 155 [95% CI, $42 382-$53 929]), and a 7.6% (95% CI, 5.6%-10.3%) mortality incidence. CM inflicts a substantial burden on hospital resources.
球孢子菌性脑膜炎（CM）需要终身积极治疗，通常需要住院治疗。在国家住院患者样本（2019 - 2021年）中，CM住院病例（N = 2305）与频繁的CM相关手术（63.6%[95%置信区间{CI}，59.3% - 67.6%]）、住院时间长（平均13.0天[95%CI，11.3 - 14.6天]）、每次住院费用高昂（平均48155美元[95%CI，42382美元 - 53929美元]）以及7.6%（95%CI，5.6% - 10.3%）的死亡率相关。CM给医院资源带来了沉重负担。
