Pang Tong, Wang Feng, Guo Qunqun, Zhang Mengjie, Sun Yuanyuan, Liu Jianguo
Key Lab of Breeding Biotechnology and Sustainable Aquaculture (CAS), CAS and Shandong Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao, China.
mBio. 2025 Jan 8;16(1):e0312024. doi: 10.1128/mbio.03120-24. Epub 2024 Dec 11.
In recent years, a disease called "Baotou" has been causing large-scale yield reductions of in China. Interestingly, , which once reported to be a probiotic or pathogen for multiple marine organisms, was strongly proved to be the pathogen causing "Baotou" disease in this study. Analysis of 16S rRNA gene profiling revealed that was the most abundant and dominant bacterium on the algal thalli suffering from "Baotou" disease, whereas its presence was scarcely detected on healthy thalli. Scanning electron microscope (SEM) analysis revealed that a large number of cells were found to be attached to the algal thalli with "Baotou" disease and the rotten thalli acquired by the lab infection treatment. could cause the rotten symptoms which were consistent with those of "Baotou" disease. According to Koch's postulates, was identified as the pathogen causing "Baotou" disease.IMPORTANCEA highly contagious disease known as "Baotou" disease has persistently triggered significant yield reductions in throughout China. The pathogen of "Baotou" disease was isolated and identified as in this study. Interestingly, was once reported to be a probiotic to , and pathogen to , , and . The study indicates that play a significant role in the competition or co-existence between , , abalone, sea urchin, bivalve, and shrimp.
近年来,一种名为“包头”的疾病在中国导致大规模减产。有趣的是,曾被报道为多种海洋生物的益生菌或病原体的[具体生物名称未给出],在本研究中被有力证明是导致“包头”病的病原体。16S rRNA基因图谱分析显示,[具体生物名称未给出]是患有“包头”病的藻体上最丰富和占主导地位的细菌,而在健康藻体上几乎检测不到其存在。扫描电子显微镜(SEM)分析表明,在患有“包头”病的藻体以及实验室感染处理后腐烂的藻体上发现大量[具体生物名称未给出]细胞附着。[具体生物名称未给出]可导致与“包头”病一致的腐烂症状。根据科赫法则,[具体生物名称未给出]被确定为导致“包头”病的病原体。
一种名为“包头”的高度传染性疾病在中国各地持续引发显著减产。本研究分离并鉴定出“包头”病的病原体为[具体生物名称未给出]。有趣的是,[具体生物名称未给出]曾被报道为[相关生物名称未给出]的益生菌,以及[相关生物名称未给出]、[相关生物名称未给出]、[相关生物名称未给出]和[相关生物名称未给出]的病原体。该研究表明,[具体生物名称未给出]在[相关生物名称未给出]、[相关生物名称未给出]、鲍鱼、海胆、双壳贝类和虾之间的竞争或共存中起重要作用。