Gong Jiali, Chen Meizhen, Luo Huamin, Li Qiuping
Nursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China; Affiliated Hospital, Jiangnan University, Wuxi, Jiangsu Province, China.
Suqian Health School in Jiangsu Province, Suqian, Jiangsu Province, China.
Eur J Oncol Nurs. 2025 Feb;74:102737. doi: 10.1016/j.ejon.2024.102737. Epub 2024 Nov 16.
This study aimed to assess the feasibility and acceptability of a couple-based self-efficacy (SE) intervention, and to examine the effects of the intervention on health outcomes for CRC couples.
An assessor-blinded, two-armed, randomized controlled design was used. The study randomly assigned 144 patients hospitalized for colorectal cancer to receive either the SE intervention or the usual care. SE was the primary outcome. The secondary outcomes included quality of life and mental health (positive emotions and negative emotions). Repeated measures analysis of variance was used to examine the data.
The recruitment and retention rates were 80% and 87.5%, respectively. First, we found that patients scored significantly higher on anxiety (p = 0.001), depression (p = 0.001) and benefit findings (p = 0.009) than did spousal caregivers, whereas spousal caregivers scored significantly higher than patients on the quality of life (p < 0.001 for both physical scores and mental scores) in the SE group. Second, immediately after the intervention, the SE group showed statistically significant improvements were found in SE (p < 0.001 for both couples), quality of life (mental scores) (p = 0.002 for spousal caregivers), negative emotion (anxiety, p < 0.05 for both couples; depression, p = 0.03 for patients), and positive emotion (benefit findings) (p < 0.001 for both couple) when compared to the control group.
A couple-based SE intervention significantly improved SE, quality of life (mental scores), and psychological well-being, suggesting a short-term intervention effect.
本研究旨在评估基于夫妻的自我效能感（SE）干预措施的可行性和可接受性，并检验该干预措施对结直肠癌患者夫妻健康结局的影响。
采用评估者盲法、双臂、随机对照设计。该研究将144名因结直肠癌住院的患者随机分为两组，分别接受SE干预或常规护理。SE为主要结局指标。次要结局指标包括生活质量和心理健康（积极情绪和消极情绪）。采用重复测量方差分析对数据进行检验。
招募率和保留率分别为80%和87.5%。首先，我们发现，在SE组中，患者在焦虑（p = 0.001）、抑郁（p = 0.001）和获益感（p = 0.009）方面的得分显著高于配偶照顾者，而配偶照顾者在生活质量方面（身体得分和心理得分均p < 0.001）显著高于患者。其次，干预后立即发现，与对照组相比，SE组在SE方面（夫妻双方p < 0.001）、生活质量（心理得分）（配偶照顾者p = 0.002）、消极情绪（焦虑，夫妻双方p < 0.05；抑郁，患者p = 0.03）和积极情绪（获益感）（夫妻双方p < 0.001）方面有统计学意义的改善。
基于夫妻的SE干预显著改善了SE、生活质量（心理得分）和心理健康，表明有短期干预效果。
