Homsi Maysam R, Davey-Rothwell Melissa A, Alonge Olakunle, Caniza Miguela A, Underwood Carol
Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA.
Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Vaccine. 2025 Jan 25;45:126578. doi: 10.1016/j.vaccine.2024.126578. Epub 2024 Dec 10.
Vaccinations are a critical component of pediatric care, protecting children, including those with cancer, from infectious complications - and significantly improving patient outcomes and survival. However, the practice and perception of vaccinating children with cancer in Latin America and the Caribbean has not been well described.
A cross-sectional survey was conducted with a convenience sample of healthcare providers involved in caring for children with cancer in Latin America and the Caribbean to establish their knowledge, attitude, and practice regarding vaccinating this special population. The electronic, self-administered survey comprised primarily close-ended questions, such as multiple-choice, Likert scale, and true/false questions, with a few open-ended questions to enable respondents to provide information not otherwise captured.
Of 384 responses received (an 11.9 % response rate), we included 378 for analysis. These respondents represented 20 countries and were, on average, aged 44.3 years with just over 14 years of practice after completing their highest level of training. Of the 378 respondents analyzed, 321 (84.9 %) recommend vaccines to their pediatric patients with cancer, with 247 (65.3 %) referring to a vaccination guideline or clinical decision tool to help plan such vaccinations and 122 (49.6 %) referring to more than one guide.
Our findings show general agreement with and support for vaccinating children with cancer, especially against influenza. Respondents reported high levels of knowledge, mostly positive attitudes, and support for recommending vaccines to patients. However, their vaccine recommendations were inconsistent. It is important to explore influential contextual factors at the institutional and governmental levels to identify strategies to increase vaccination coverage of children with cancer in the region.
疫苗接种是儿科护理的关键组成部分,可保护儿童(包括癌症患儿)免受感染性并发症的侵害,并显著改善患者的治疗效果和生存率。然而,拉丁美洲和加勒比地区癌症患儿疫苗接种的实际情况和认知尚未得到充分描述。
对拉丁美洲和加勒比地区参与照顾癌症患儿的医疗服务提供者进行了一项横断面调查,以了解他们对这一特殊人群疫苗接种的知识、态度和做法。这项电子自填式调查主要包括封闭式问题,如多项选择题、李克特量表和是非题,还有一些开放式问题,以便受访者提供其他未涵盖的信息。
共收到384份回复(回复率为11.9%),其中378份纳入分析。这些受访者来自20个国家,平均年龄44.3岁,在完成最高水平培训后平均有超过14年的工作经验。在分析的378名受访者中,321人(84.9%)向他们的儿科癌症患者推荐疫苗,其中247人(65.3%)参考疫苗接种指南或临床决策工具来帮助规划此类疫苗接种,122人(49.6%)参考了不止一份指南。
我们的研究结果表明,对于癌症患儿接种疫苗,尤其是接种流感疫苗,普遍达成了共识并给予支持。受访者报告称知识水平较高,态度大多积极,并支持向患者推荐疫苗。然而,他们的疫苗推荐并不一致。探索机构和政府层面的影响因素,以确定提高该地区癌症患儿疫苗接种覆盖率的策略非常重要。