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轴性脊柱关节炎早期诊断与管理的成像技术进展

Advancements in Imaging Techniques for Early Diagnosis and Management of Axial Spondyloarthritis.

作者信息

Jeon Howook, Min Hong Ki

机构信息

Division of Rheumatology, Department of Internal Medicine, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.

Division of Rheumatology, Department of Internal Medicine, Research Institute of Medical Science, Konkuk University School of Medicine, 120-1 Neungdong-ro (Hwayang-dong), Gwangjin-gu, Seoul, 143-729, Republic of Korea.

出版信息

Curr Rheumatol Rep. 2024 Dec 12;27(1):7. doi: 10.1007/s11926-024-01172-7.

Abstract

PURPOSE OF REVIEW

We aimed to introduce recent finding of imaging studies used in axial spondyloarthritis (axSpA).

RECENT FINDINGS

Using low-dose whole spine CT (CT syndesmophyte score [CTSS]) improved diagnostic accuracy for evaluating spinal structural progression than previous method (modified Stoke Ankylosing Spondylitis Spinal Score [mSASSS]) in axSpA. The novel definition of positive finding of sacroiliac joint (SIJ) and spine magnetic resonance imaging (MRI) enabled to diagnose axSpA earlier than plain radiography. In addition, novel MRI protocol such as volumetric interpolated breath-hold examination improved detection rate of structural change of axial joints in axSpA, Nuclear medicine imaging showed potential for diagnosis and predicting progression of axSpA. Ultrasonography guided injection is useful for controlling local joint pain of axSpA. AxSpA is characterised by pain and inflammation of axial joints such as the SIJ and spine. Detection of active inflammatory lesions using MRI has expanded the subtypes of axSpA to include non-radiographic axSpA (nr-axSpA). In addition, many other imaging techniques have improved, and can now detect structural and early inflammatory lesions of the axial joints. In addition, a method for quantitative measurement of syndesmophytes by CTSS has been developed; this method is more accurate and sensitive than the mSASSS for detecting spinal structural damage. Here, we discuss the current knowledge and clinical advances in computed tomography, MRI, nuclear medicine imaging, and ultrasonography as imaging methods for axSpA.

摘要

综述目的

我们旨在介绍轴向型脊柱关节炎(axSpA)中影像学研究的最新发现。

最新发现

在axSpA中,使用低剂量全脊柱CT(CT韧带骨赘评分[CTSS])比以前的方法(改良斯托克强直性脊柱炎脊柱评分[mSASSS])在评估脊柱结构进展方面提高了诊断准确性。骶髂关节(SIJ)和脊柱磁共振成像(MRI)阳性发现的新定义使得能够比普通X线摄影更早地诊断axSpA。此外,诸如容积内插屏气检查等新型MRI方案提高了axSpA中轴关节结构变化的检出率,核医学成像显示出在axSpA诊断和预测疾病进展方面的潜力。超声引导下注射有助于控制axSpA的局部关节疼痛。AxSpA的特征是SIJ和脊柱等轴关节的疼痛和炎症。使用MRI检测活动性炎症病变已将axSpA的亚型扩展到包括非放射学axSpA(nr-axSpA)。此外,许多其他成像技术也有所改进,现在能够检测轴关节的结构和早期炎症病变。此外,已经开发出一种通过CTSS对韧带骨赘进行定量测量的方法;该方法在检测脊柱结构损伤方面比mSASSS更准确、更敏感。在此,我们讨论计算机断层扫描、MRI、核医学成像和超声检查作为axSpA成像方法的当前知识和临床进展。

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