Yoo Seok Ju, Min Hye Kyu, Kim Sung Wan, Min Jin-Young
Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
J Rhinol. 2024 Jul;31(2):119-123. doi: 10.18787/jr.2024.00016. Epub 2024 Jul 31.
Tuberculosis of the paranasal sinus is a rare disease caused by infection with Mycobacterium tuberculosis, the causative agent of pulmonary tuberculosis. Although the worldwide incidence of tuberculosis is declining, the diagnosis of primary paranasal tuberculosis remains challenging and cannot be ruled out in patients presenting with refractory chronic rhinosinusitis after adequate surgical and medical treatment. We experienced a case of paranasal tuberculosis with no evidence of previous tuberculosis infection. It was diagnosed after a surgical biopsy revealed granulomatous inflammation and caseous necrosis. The patient responded well to antituberculosis drug therapy and became free of symptoms after 7 months of treatment. We report our findings in this case with a review of the recent literature.
鼻窦结核是一种由结核分枝杆菌感染引起的罕见疾病,结核分枝杆菌也是肺结核的病原体。尽管全球结核病发病率在下降,但原发性鼻窦结核的诊断仍然具有挑战性,对于经过充分手术和药物治疗后仍患有难治性慢性鼻窦炎的患者,不能排除该病。我们遇到一例鼻窦结核患者,此前无结核病感染证据。手术活检显示肉芽肿性炎症和干酪样坏死,据此得以确诊。该患者对抗结核药物治疗反应良好,治疗7个月后症状消失。我们报告该病例的研究结果,并对近期文献进行综述。