Lee Ju Eun, Hwang Se Hwan
Department of Otolaryngology-Head and Neck Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
J Rhinol. 2023 Mar;30(1):48-52. doi: 10.18787/jr.2023.00008. Epub 2023 Mar 30.
IgG4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by IgG4-positive plasma cell and T lymphocyte infiltration of multiple organs. It commonly involves the pancreas, lacrimal glands, and salivary glands, and it has been rarely reported in the sinonasal cavity. We herein report the case of a 47-year-old male patient whose chief complaint was decreased visual acuity. A tumefactive mass was found on imaging studies, originating from the sinonasal cavity and invading the orbit, kidney, and meninges. The mass was resected through endoscopic sinus surgery and was pathologically confirmed to be IgG4-RD. The patient was treated with steroid therapy and showed clinical improvement.
IgG4相关疾病（IgG4-RD）是一种全身性炎症性疾病，其特征为多个器官出现IgG4阳性浆细胞和T淋巴细胞浸润。它通常累及胰腺、泪腺和唾液腺，而在鼻窦腔中鲜有报道。我们在此报告一例47岁男性患者，其主要诉求为视力下降。影像学检查发现一个肿块，起源于鼻窦腔并侵犯眼眶、肾脏和脑膜。通过鼻内镜鼻窦手术切除该肿块，病理证实为IgG4-RD。患者接受了类固醇治疗并显示出临床改善。
