Su Hui, Huo Yunyun, Li Baomin, Lv Bin, Zhang Rongju, Du Zhihua, Liu Xinfeng, Wang Jun, Chen Xing, Cao Xiangyu
Department of Neurology, Chinese PLA General Hospital, First medical center, Beijing, China.
Beijing Advanced Innovation Center for Biomedical Engineering, School of Engineering Medicine, Beihang University, Beijing, China.
Otol Neurotol. 2025 Jan 1;46(1):112-117. doi: 10.1097/MAO.0000000000004365.
To investigate the long-term outcomes of stenting for isolated pulsatile tinnitus (PT) caused by cerebral venous sinus stenosis.
Retrospective study.
The First Medical Center, Chinese PLA General Hospital.
Patients diagnosed to have isolated PT secondary to cerebral venous sinus stenosis at our institution between December 2009 and March 2023.
Cerebral venous sinus stenting.
Morphological features of the cerebral venous sinus, endovascular technique, and clinical outcomes.
The study included 80 patients with a mean age of 39.4 ± 9.6 years and an average body mass index of 23.9 kg/m. The mean age at symptom onset was 35.1 ± 8.7 years. Seventy-five of the patients (93.8%) were women. PT was the primary symptom. All patients reported feeling anxious because PT had severely affected their day-to-day lives. The PT was right-sided in 52 cases (65%). All procedures were technically successful. The mean trans-stenotic pressure gradient decreased from 4.3 ± 3.3 mm Hg before stenting to 0.4 ± 0.9 mm Hg after stent placement. Twenty-one patients (26.3%) experienced poststenting headache. The mean follow-up duration was 80.5 ± 46.3 months, with 26 patients followed for over 120 months. PT resolved in all cases after stenting, and there were no recurrences. Follow-up radiographic examination of 23 patients (28.8%) at a mean of 71.2 ± 43.1 months identified only one case of restenosis.
Long-term follow-up of these patients confirmed the efficacy and safety of stenting for isolated venous sinus stenosis-related PT.
探讨脑静脉窦狭窄所致孤立性搏动性耳鸣（PT）支架置入术的长期疗效。
回顾回顾性研究设计：回顾性研究。
中国人民解放军总医院第一医学中心。
2009年12月至2023年3月期间在我院被诊断为继发于脑静脉窦狭窄的孤立性PT患者。
脑静脉窦支架置入术。
脑静脉窦的形态学特征、血管内技术及临床疗效。
本研究纳入80例患者，平均年龄39.4±9.6岁，平均体重指数23.9kg/m²。症状出现的平均年龄为35.1±8.7岁。其中75例（93.8%）为女性。PT为主要症状。所有患者均表示因PT严重影响日常生活而感到焦虑。52例（65%）患者的PT位于右侧。所有手术在技术上均获成功。平均跨狭窄压力梯度从支架置入术前的4.3±3.3mmHg降至支架置入后的0.4±0.9mmHg。21例（26.3%）患者术后出现头痛。平均随访时间为80.5±46.3个月，其中26例患者随访时间超过120个月。支架置入术后所有病例的PT均消失，且无复发。对23例（28.8%）患者平均在71.2±43.1个月时进行的随访影像学检查仅发现1例再狭窄。
对这些患者的长期随访证实了支架置入术治疗孤立性静脉窦狭窄相关PT的有效性和安全性。
