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美国人工耳蜗植入联盟关于新生儿先天性巨细胞病毒筛查的立场声明。

American Cochlear Implant Alliance Position Statement on Newborn Congenital Cytomegalovirus Screening.

作者信息

Pesch Megan Honor, Brown Kevin David, Birath Amy L, Demmler-Harrison Gail J, Sapp Cailtin, Selleck Anne Morgan, Sweeney Alex D

机构信息

Division of Developmental and Behavioral Pediatrics, Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.

National CMV Foundation, Tampa, Florida, USA.

出版信息

Otolaryngol Head Neck Surg. 2025 Feb;172(2):728-733. doi: 10.1002/ohn.1079. Epub 2024 Dec 12.

DOI:10.1002/ohn.1079
PMID:39666828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11773442/
Abstract

It is estimated that 1 in every 200 US newborns has congenital cytomegalovirus (cCMV). Delayed identification of cCMV in newborns precludes timely intervention to mitigate sequelae of the infection such as hearing loss and other neurological complications. Newborn testing for cCMV enables appropriate diagnosis and intervention by multidisciplinary teams to properly manage the immediate sequelae of cCMV, avoid unnecessary additional testing that can result from delayed diagnosis, and monitor for future complications. It is the position of the American Cochlear Implant Alliance, the National CMV Foundation, and the American Academy of Otolaryngology-Head and Neck Surgery that universal newborn cCMV screening is necessary to best accomplish these goals.

摘要

据估计,美国每200名新生儿中就有1人患有先天性巨细胞病毒(cCMV)。新生儿cCMV的延迟识别会妨碍及时干预,以减轻感染的后遗症,如听力损失和其他神经并发症。对新生儿进行cCMV检测可使多学科团队进行适当的诊断和干预,以妥善处理cCMV的直接后遗症,避免因诊断延迟而导致的不必要的额外检测,并监测未来的并发症。美国人工耳蜗植入联盟、全国CMV基金会和美国耳鼻咽喉-头颈外科学会的立场是,普遍的新生儿cCMV筛查对于最好地实现这些目标是必要的。

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Autism Spectrum Disorder Diagnoses and Congenital Cytomegalovirus.自闭症谱系障碍诊断与先天性巨细胞病毒。
Pediatrics. 2024 Jun 1;153(6). doi: 10.1542/peds.2023-064081.
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Epidemiology, aetiology and diagnosis of congenital hearing loss via hearing screening of 153 913 newborns.对 153913 例新生儿进行听力筛查以了解先天性听力损失的流行病学、病因学和诊断。
Int J Epidemiol. 2024 Apr 11;53(3). doi: 10.1093/ije/dyae052.
3
Congenital Cytomegalovirus Testing Outcomes From the ValEAR Trial.ValEAR试验的先天性巨细胞病毒检测结果
Otolaryngol Head Neck Surg. 2024 May;170(5):1430-1441. doi: 10.1002/ohn.670. Epub 2024 Feb 28.
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Valganciclovir in Infants with Hearing Loss and Clinically Inapparent Congenital Cytomegalovirus Infection: A Nonrandomized Controlled Trial.缬更昔洛韦治疗伴有听力损失和临床无症状先天性巨细胞病毒感染的婴儿:一项非随机对照试验。
J Pediatr. 2024 May;268:113945. doi: 10.1016/j.jpeds.2024.113945. Epub 2024 Feb 8.
5
Utility of Dried Blood Spots for the Diagnosis of Congenital Cytomegaloviruses within the First 21 Days of Life in a Single Center.干血斑在单中心出生后21天内先天性巨细胞病毒诊断中的应用
Int J Neonatal Screen. 2023 Aug 4;9(3):44. doi: 10.3390/ijns9030044.
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