Hodson G R, Urdaneta L F, Al-Jurf A S, Jochimsen P R
Am Surg. 1985 Jan;51(1):47-9.
Fifty men with primary breast carcinoma were seen between the years 1938 and 1983 at the University of Iowa Hospitals and Clinics. In most patients, there was a significant delay between the onset of symptoms and seeking medical advice (mean, 21 months; range, 1-156). The vast majority of patients were treated by simple, modified radical, or radical mastectomy. Ten patients underwent incisional or excisional biopsy with or without radiation because of locally advanced disease or distant metastases. Survival was comparable in the groups of patients treated with simple mastectomy (mean, 70 months), modified radical mastectomy (mean, 61 months), and radical mastectomy (mean, 78 months). Local recurrence occurred in 25 per cent of all patients, and this rate was not dependent on the operation performed. The data suggest that modified radical mastectomy is adequate therapy for local control and staging of the disease without reducing survival from that observed after radical mastectomy.
1938年至1983年间,爱荷华大学医院及诊所共收治了50例原发性乳腺癌男性患者。大多数患者在出现症状后很久才就医(平均21个月,范围1 - 156个月)。绝大多数患者接受了单纯乳房切除术、改良根治性乳房切除术或根治性乳房切除术。10例患者因局部晚期疾病或远处转移接受了切除活检或切除活检联合放疗。接受单纯乳房切除术(平均70个月)、改良根治性乳房切除术(平均61个月)和根治性乳房切除术(平均78个月)的患者组生存率相当。25%的患者出现局部复发,且该复发率与所施行的手术无关。数据表明,改良根治性乳房切除术足以实现疾病的局部控制和分期,且不会降低生存率,与根治性乳房切除术后的生存率相当。