Hariyanto A P, Mugni F F, Khumaira L, Sensusiati A D, Nursela A L, Ng K H, Haryanto F
Department of Physics, Institut Teknologi Sepuluh Nopember, Kampus ITS, Sukolilo Surabaya 60111, East Java, Indonesia.
Department of Radiology, Universitas Airlangga Hospital, Surabaya 60115, East Java, Indonesia.
Radiography (Lond). 2025 Jan;31(1):254-263. doi: 10.1016/j.radi.2024.11.023. Epub 2024 Dec 11.
Phantom materials with tissue-equivalent physical properties that require regular evaluation using patented phantoms are essential for medical device quality assurance programs. This study evaluated phantom materials for tissue equivalence and their use in image quality assessment for breast ultrasound scanner performance testing using two custom-made phantoms.
Two types of phantoms were developed: phantoms A and B. Phantom A was made from a base material consisting of polyvinyl chloride-plastisol with the addition of glycerol, whereas phantom B consisted of polyvinyl chloride-plastisol with the addition of graphite. Each phantom had a stiff and soft lesion shaped like a sphere, with a diameter of 1.4 cm. The phantoms were cuboids with dimensions of 10 × 10 cm and a thickness of 5 cm. A series of phantom evaluations was performed, consisting of density, elasticity, acoustic properties, B-mode ultrasound images, and strain ratio.
The characterisation results show that background A closely resembles fibroglandular tissue in terms of density and acoustic properties (<5% variation); background B only resembles fibroglandular tissue in terms of density (-1.8% variation). In terms of elasticity, both backgrounds were close to the minimum value of fibroglandular tissue elasticity. The soft lesion on the phantom had a slightly lower density and elasticity than the carcinoma, whereas its acoustic properties (speed of sound and attenuation coefficient) were slightly higher than those of the reference carcinoma. Both phantoms were consistent with the literature in terms of strain ratio, geometric accuracy, lesion detection, and mean pixel value and showed good potential stability over one year.
This study successfully described the fabrication and evaluation sequence of a phantom equivalent to breast fibroglandular tissue and its evaluation via ultrasound imaging.
This study offers proprietary information essential for the fabrication of phantoms that can be used for quality assurance and control in ultrasound imaging.
具有组织等效物理特性的体模材料对于医疗设备质量保证计划至关重要，需要使用专利体模进行定期评估。本研究使用两个定制体模评估了用于组织等效性的体模材料及其在乳腺超声扫描仪性能测试的图像质量评估中的应用。
开发了两种类型的体模：体模A和体模B。体模A由聚氯乙烯增塑溶胶制成的基础材料添加甘油制成，而体模B由聚氯乙烯增塑溶胶添加石墨制成。每个体模都有一个直径为1.4厘米的球形硬病变和软病变。体模为长方体，尺寸为10×10厘米，厚度为5厘米。进行了一系列体模评估，包括密度、弹性、声学特性、B型超声图像和应变率。
表征结果表明，背景A在密度和声学特性方面与纤维腺组织非常相似（变化<5%）；背景B仅在密度方面与纤维腺组织相似（变化-1.8%）。在弹性方面，两种背景都接近纤维腺组织弹性的最小值。体模上的软病变密度和弹性略低于癌组织，而其声学特性（声速和衰减系数）略高于参考癌组织。两种体模在应变率、几何精度、病变检测和平均像素值方面与文献一致，并且在一年中显示出良好的潜在稳定性。
本研究成功描述了一种等效于乳腺纤维腺组织的体模的制造和评估过程及其通过超声成像的评估。
本研究提供了制造可用于超声成像质量保证和控制的体模所需的专有信息。
