Kumar N Kiran, M Abhishek, B Naik Savitha, Brigit Biji, V Swetha Geervani, Manimozhi M
Department of Conservative Dentistry & Endodontics, Government Dental College and Research Institute, Fort, Bangalore, India.
Photobiomodul Photomed Laser Surg. 2025 Feb;43(2):53-58. doi: 10.1089/photob.2024.0090. Epub 2024 Dec 12.
The evaluation of the effect of laser in disinfection of root canal in pulp regenerative therapy, if found effective laser can be used for root canal disinfection in cases of regenerative endodontic therapy. This study includes a systematic review addressing the question of whether laser is effective in root canal treatment in regenerative endodontic therapy. Randomized controlled trials (RCTs), case series, and animal studies evaluating the effect of laser-assisted endodontic irrigation in pulp regenerative therapy were included. Review articles, case reports, and in vitro studies were excluded. The data search covers all publications without limitation by year. The last search was conducted on December 31, 2023. An electronic search was performed using the following databases: PubMed, Cochrane Library, and Google Scholar. The result of this review was in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. Assessment of risk of bias was done using the modified Cochrane Risk of Bias Tool. The initial search resulted in 749 articles. Eleven duplicate articles were removed. Following the titles and abstracts screening, 11 articles were identified to form the basis of this systematic review. Three articles were excluded as full text was unavailable. Overall, eight studies evaluated the laser effect in root canal disinfection in pulp regenerative therapy, which were included in this systematic review. Of the included studies, a low risk of bias was shown by 7/8 studies, and a moderate risk of bias was shown by 1/8 studies. Laser can be used for root canal disinfection in cases of regenerative endodontic therapy. There is a need for further RCTs about individual laser groups and their disinfection effect on regenerative endodontic therapy for obtaining a higher level of evidence.
评估激光在牙髓再生治疗中根管消毒的效果，若发现有效，则可用于再生性牙髓治疗中的根管消毒。本研究包括一项系统评价，探讨激光在再生性牙髓治疗的根管治疗中是否有效的问题。纳入了评估激光辅助根管冲洗在牙髓再生治疗中效果的随机对照试验（RCT）、病例系列和动物研究。排除综述文章、病例报告和体外研究。数据检索涵盖所有年份的出版物，无年份限制。最后一次检索于2023年12月31日进行。使用以下数据库进行电子检索：PubMed、Cochrane图书馆和谷歌学术。本综述结果符合系统评价和Meta分析的首选报告项目指南。使用改良的Cochrane偏倚风险工具进行偏倚风险评估。初步检索得到749篇文章，去除11篇重复文章。经过标题和摘要筛选，确定11篇文章作为本系统评价的基础。因无法获取全文而排除3篇文章。总体而言，8项研究评估了激光在牙髓再生治疗中根管消毒的效果，这些研究被纳入本系统评价。在纳入的研究中，7/8的研究显示偏倚风险较低，1/8的研究显示偏倚风险中等。激光可用于再生性牙髓治疗中的根管消毒。需要进一步开展关于各个激光组及其对再生性牙髓治疗消毒效果的随机对照试验，以获得更高水平的证据。
