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机器人辅助腹腔镜根治性前列腺切除术中患者体位对术后神经病变的影响:一项随机对照试验

Impact of patient positioning during surgery on neuropathies after robot-assisted laparoscopic radical prostatectomy: a randomised controlled trial.

作者信息

Grossmann Nico Christian, Aschwanden Fabian Joel, Cornelius Julian, Malkmus Christian, Zahiti Leutrim, Viktorin Pascal, Fierley Lea, Wilder-Smith Einar, Baumeister Philipp, Mattei Agostino, Fankhauser Christian Daniel

机构信息

Department of Urology, Kantonsspital Luzern, Lucerne, Switzerland.

University of Lucerne, Lucerne, Switzerland.

出版信息

BJU Int. 2025 May;135(5):802-809. doi: 10.1111/bju.16623. Epub 2024 Dec 12.

Abstract

OBJECTIVE

To investigate whether ankle braces or shoulder support used for fixation during robot-assisted radical prostatectomy (RARP), where patients are commonly positioned in the head-down Trendelenburg position, differ in their potential to cause peripheral nerve injury.

PATIENTS AND METHODS

A prospective, double-blind, randomised controlled trial was conducted on patients undergoing RARP for prostate cancer between May 2020 and September 2021 using the da Vinci Si system (Intuitive Surgical Inc., Sunnyvale, CA, USA). Patients were randomly assigned to either the shoulder or ankle brace fixation group and were positioned in a modified lithotomy position. Neurological examinations were performed pre- and postoperatively. The primary endpoint was the prevalence of any peripheral neuropathy on the first postoperative day.

RESULTS

A total of 98 patients were treated using the da Vinci Si system: 46 in the lithotomy lower fixation group and 52 in the lithotomy upper fixation group. Both groups mainly recorded neuropathies in the lower extremity, with a total incidence of 6.9% for lower neuropathies and 3.9% for upper neuropathies. All neuropathies were sensory, with one exception in the upper fixation group presenting a motor deficit. Over a median follow-up of 12 months, no neuropathies persisted. Neuropathy on the first postoperative day was observed in 15% of patients in the upper fixation group and 6.5% in the lower fixation group (P = 0.2).

CONCLUSION

We observed neuropathies in a clinically relevant proportion of men undergoing RARP. We were not able to demonstrate a significant difference regarding postoperative neuropathies between ankle braces or shoulder support during RARP.

摘要

目的

探讨在机器人辅助根治性前列腺切除术(RARP)中,患者通常处于头低脚高位时,用于固定的踝部支具或肩部支撑物导致周围神经损伤的可能性是否存在差异。

患者与方法

对2020年5月至2021年9月期间使用达芬奇Si系统(美国加利福尼亚州森尼韦尔市直观外科公司)接受RARP治疗前列腺癌的患者进行了一项前瞻性、双盲、随机对照试验。患者被随机分配至肩部或踝部支具固定组,并采用改良截石位。术前和术后均进行神经学检查。主要终点是术后第一天任何周围神经病变的发生率。

结果

共有98例患者使用达芬奇Si系统进行治疗:截石位下肢固定组46例,截石位上肢固定组52例。两组主要记录的是下肢神经病变,下肢神经病变总发生率为6.9%,上肢神经病变总发生率为3.9%。所有神经病变均为感觉性,上肢固定组有1例出现运动功能障碍。中位随访12个月时,无神经病变持续存在。上肢固定组15%的患者在术后第一天出现神经病变,下肢固定组为6.5%(P = 0.2)。

结论

我们在接受RARP的男性患者中观察到了具有临床相关性比例的神经病变。我们未能证明RARP期间踝部支具或肩部支撑在术后神经病变方面存在显著差异。

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