Enderby D H, Boylett A, Parker D J
Thorax. 1979 Dec;34(6):720-5. doi: 10.1136/thx.34.6.720.
Thirty-one patients who were undergoing cardiopulmonary bypass for elective aortic valve replacement were studied. The effects on some aspects of lung function of intravenous methyl prednisolone, administered immediately before bypass, were assessed by measuring alveolar-arterial oxygen differences and shunt fractions. No significant differences in pulmonary function were found between the treated and control groups. The use of methyl prednisolone in this context is not justified.
对31例接受择期主动脉瓣置换术并进行体外循环的患者进行了研究。通过测量肺泡-动脉氧分压差和分流分数,评估了在体外循环前即刻静脉注射甲基泼尼松龙对肺功能某些方面的影响。治疗组和对照组之间在肺功能方面未发现显著差异。在这种情况下使用甲基泼尼松龙是不合理的。