Anderson G, Jariwalla A G, Saour J
Thorax. 1979 Dec;34(6):814-6. doi: 10.1136/thx.34.6.814.
Twenty-five patients with an acute exacerbation of chronic bronchitis completed a double-blind trial of amoxycillin 1.5 g v ampicillin 4 g daily. After treatment for one week there was no difference between the treatments in the rates of achieving mucoid sputum, reduction in sputum volume, improvement in peak expiratory flow rate, or duration of hospital stay. In the doses studied ampicillin and amoxycillin are effective drugs of about equal cost.
25例慢性支气管炎急性加重患者完成了一项阿莫西林1.5克与氨苄西林4克每日剂量的双盲试验。治疗一周后,在产生黏液样痰的比例、痰量减少情况、呼气峰值流速改善情况或住院时间方面,两种治疗方法之间没有差异。在所研究的剂量下,氨苄西林和阿莫西林是成本大致相当的有效药物。