Di Marco Luca, Nocera Chiara, Buia Francesco, Campanini Francesco, Attinà Domenico, Murana Giacomo, Lovato Luigi, Pacini Davide
Cardiac Surgery Unit, Department of Medical and Surgical Sciences, DIMEC, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Department of Medical and Surgical Sciences, DIMEC, University of Bologna, Bologna, Italy.
JTCVS Tech. 2024 Sep 16;28:1-7. doi: 10.1016/j.xjtc.2024.08.025. eCollection 2024 Dec.
In the last few years, fenestrated, branched, or scalloped custom grafts have become available for aortic arch repair. Open surgery is the gold standard, but arch thoracic endovascular aortic repair (TEVAR) is indicated for high-risk patients. We focused on total endovascular aortic arch replacement with a zone 0 or zone 1 landing zone to describe its short- and long-term outcomes.
We retrospectively analyzed patients who underwent arch TEVAR with a zone 0 or zone 1 landing zone at our center. We then performed a Kaplan-Meier analysis for survival and freedom from reintervention at follow-up.
From May 2017 to November 2023, 15 patients underwent elective arch TEVAR, having been deemed unfit for open surgery. Mean age was 74.7 ± 7.8 years. The most frequent procedure was fenestrated endovascular aortic repair with a left carotid-subclavian bypass (LCSB) (6; 40%), followed by double-branched graft with LCSB (5; 33.3%) and triple-branched graft (2; 13.3%) and scalloped graft with LCSB (2; 13.3%). There was 1 in-hospital death (6.7%). Perioperative stroke occurred in 2 cases (13.3%). Mean follow-up (FU) time was 16.4 ± 15.1 months. There were 3 deaths at FU, all for noncardiovascular causes, and 1 stroke at FU. One patient required further stenting of the brachiocephalic trunk for a type III endoleak. Survival at 12 months was 87.5% and freedom from reintervention was 85.7%.
Total endovascular aortic arch repair with custom-made prosthesis is a safe and effective procedure in patients with prohibitive surgical risk. Stroke remains the main complication with significant rates.
在过去几年中,开窗、分支或带扇贝边的定制移植物已可用于主动脉弓修复。开放手术是金标准,但对于高危患者,胸主动脉腔内修复术(TEVAR)是适用的。我们重点关注采用0区或1区着陆区的全腔内主动脉弓置换术,以描述其短期和长期结果。
我们回顾性分析了在本中心接受采用0区或1区着陆区的弓部TEVAR的患者。然后我们对随访时的生存率和免于再次干预情况进行了Kaplan-Meier分析。
2017年5月至2023年11月,15例患者接受了择期弓部TEVAR,被认为不适合进行开放手术。平均年龄为74.7±7.8岁。最常见的手术是带左颈动脉-锁骨下动脉旁路(LCSB)的开窗腔内主动脉修复术(6例;40%),其次是带LCSB的双分支移植物(5例;33.3%)、三分支移植物(2例;13.3%)和带LCSB的带扇贝边移植物(2例;13.3%)。有1例住院死亡(6.7%)。围手术期发生2例卒中(13.3%)。平均随访时间为16.4±15.1个月。随访时有3例死亡,均为非心血管原因,随访时有1例卒中。1例患者因III型内漏需要对头臂干进一步置入支架。12个月时的生存率为87.5%,免于再次干预率为85.7%。
对于手术风险极高的患者,采用定制假体进行全腔内主动脉弓修复是一种安全有效的手术。卒中仍然是主要并发症,发生率较高。