Kim Hyo-Shin, Kim Da-Hyun, Kim Dong-Ik, Park Joon-Kee, Yang Shin-Seok, Park Yang-Jin
Division of Vascular Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Ann Surg Treat Res. 2024 Dec;107(6):315-326. doi: 10.4174/astr.2024.107.6.315. Epub 2024 Dec 2.
The Vascular Study Group of New England (VSGNE) risk prediction model is a simple method for estimating risk for elective abdominal aortic aneurysm (AAA) repair. The model considers both treatment methods and the physical characteristics of the aneurysm type as well as comorbidities. This research aimed to validate its effectiveness by analyzing retrospective data on Korean patients.
Our single-center retrospective analysis included 1,227 patients who underwent elective open repair surgery (ORS) or endovascular aortic repair (EVAR) from 2005 to 2021. We assessed the discrimination of the risk score and the effects of several risk factors.
Most patients (66.7%) were classified as low risk in the model, with only 5.6% considered high risk. The mean risk score was 2.81, significantly lower than reported in previous studies. The actual 30-day mortality was only 0.7%, less than the predicted 1.1%. The accuracy of the model in predicting 30-day mortality was statistically significant (area under the curve, 0.822). Patients with high scores were associated with significantly increased mortality (odds ratio, 3.9; P < 0.001). Factors such as advanced age, cerebrovascular disease, and elevated creatinine levels were influential in mortality outcomes. However, a significant difference was not found in short-term mortality between ORS and EVAR.
Although the VSGNE model is an objective tool for assessing death risk in elective AAA repair, the actual risk scores in our patient population were lower than predicted. To create a more representative tool for the Korean population, we suggest developing a novel model based on multicenter data collection.
新英格兰血管研究组(VSGNE)风险预测模型是一种用于评估择期腹主动脉瘤(AAA)修复风险的简单方法。该模型既考虑了治疗方法、动脉瘤类型的物理特征,也考虑了合并症。本研究旨在通过分析韩国患者的回顾性数据来验证其有效性。
我们的单中心回顾性分析纳入了2005年至2021年期间接受择期开放修复手术(ORS)或血管腔内主动脉修复(EVAR)的1227例患者。我们评估了风险评分的辨别能力以及几个风险因素的影响。
在该模型中,大多数患者(66.7%)被归类为低风险,只有5.6%被认为是高风险。平均风险评分为2.81,显著低于先前研究报告的水平。实际30天死亡率仅为0.7%,低于预测的1.1%。该模型预测30天死亡率的准确性具有统计学意义(曲线下面积为0.822)。高分患者的死亡率显著增加(优势比为3.9;P<0.001)。高龄、脑血管疾病和肌酐水平升高之类的因素对死亡率结果有影响。然而,ORS和EVAR之间的短期死亡率未发现显著差异。
尽管VSGNE模型是评估择期AAA修复死亡风险的客观工具,但我们患者群体的实际风险评分低于预测值。为了创建一个更具代表性的韩国人群工具,我们建议基于多中心数据收集开发一种新模型。