Suppr超能文献

新英格兰血管研究组(VSGNE)腹主动脉瘤修复风险预测模型在韩国的验证:一项单中心回顾性研究。

Validation of the Vascular Study Group of New England (VSGNE) risk prediction model for abdominal aortic aneurysm repair in Korea: a single-center retrospective study.

作者信息

Kim Hyo-Shin, Kim Da-Hyun, Kim Dong-Ik, Park Joon-Kee, Yang Shin-Seok, Park Yang-Jin

机构信息

Division of Vascular Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Ann Surg Treat Res. 2024 Dec;107(6):315-326. doi: 10.4174/astr.2024.107.6.315. Epub 2024 Dec 2.

Abstract

PURPOSE

The Vascular Study Group of New England (VSGNE) risk prediction model is a simple method for estimating risk for elective abdominal aortic aneurysm (AAA) repair. The model considers both treatment methods and the physical characteristics of the aneurysm type as well as comorbidities. This research aimed to validate its effectiveness by analyzing retrospective data on Korean patients.

METHODS

Our single-center retrospective analysis included 1,227 patients who underwent elective open repair surgery (ORS) or endovascular aortic repair (EVAR) from 2005 to 2021. We assessed the discrimination of the risk score and the effects of several risk factors.

RESULTS

Most patients (66.7%) were classified as low risk in the model, with only 5.6% considered high risk. The mean risk score was 2.81, significantly lower than reported in previous studies. The actual 30-day mortality was only 0.7%, less than the predicted 1.1%. The accuracy of the model in predicting 30-day mortality was statistically significant (area under the curve, 0.822). Patients with high scores were associated with significantly increased mortality (odds ratio, 3.9; P < 0.001). Factors such as advanced age, cerebrovascular disease, and elevated creatinine levels were influential in mortality outcomes. However, a significant difference was not found in short-term mortality between ORS and EVAR.

CONCLUSION

Although the VSGNE model is an objective tool for assessing death risk in elective AAA repair, the actual risk scores in our patient population were lower than predicted. To create a more representative tool for the Korean population, we suggest developing a novel model based on multicenter data collection.

摘要

目的

新英格兰血管研究组(VSGNE)风险预测模型是一种用于评估择期腹主动脉瘤(AAA)修复风险的简单方法。该模型既考虑了治疗方法、动脉瘤类型的物理特征,也考虑了合并症。本研究旨在通过分析韩国患者的回顾性数据来验证其有效性。

方法

我们的单中心回顾性分析纳入了2005年至2021年期间接受择期开放修复手术(ORS)或血管腔内主动脉修复(EVAR)的1227例患者。我们评估了风险评分的辨别能力以及几个风险因素的影响。

结果

在该模型中,大多数患者(66.7%)被归类为低风险,只有5.6%被认为是高风险。平均风险评分为2.81,显著低于先前研究报告的水平。实际30天死亡率仅为0.7%,低于预测的1.1%。该模型预测30天死亡率的准确性具有统计学意义(曲线下面积为0.822)。高分患者的死亡率显著增加(优势比为3.9;P<0.001)。高龄、脑血管疾病和肌酐水平升高之类的因素对死亡率结果有影响。然而,ORS和EVAR之间的短期死亡率未发现显著差异。

结论

尽管VSGNE模型是评估择期AAA修复死亡风险的客观工具,但我们患者群体的实际风险评分低于预测值。为了创建一个更具代表性的韩国人群工具,我们建议基于多中心数据收集开发一种新模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/628a/11634392/79443efae5a6/astr-107-315-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验