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无细胞阑尾黏液性肿瘤

Acellular Appendix Vermiform Mucinous Neoplasm.

作者信息

Tsikouras Panagiotis, Tsalikidis Christos, Oikonomou Efthymios, Kouroupi Maria, Nikolettos Konstantinos, Bothou Anastasia, Nalmpanti Theopi, Kritsotaki Nektaria, Kotanidou Sonia, Iatrakis Georgios, Nikolettos Nikolaos

机构信息

Department of Obstetrics and Gynecology, Democritus University of Thrace, Alexandroupolis, Greece.

Second Department of Surgery, University General Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece.

出版信息

Case Rep Pathol. 2024 Dec 5;2024:7732249. doi: 10.1155/crip/7732249. eCollection 2024.

DOI:10.1155/crip/7732249
PMID:39669795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11637618/
Abstract

Appendiceal neoplasms are usually asymptomatic or associated with mild, nonspecific symptoms. Due to the rarity of the disease and the lack of specific symptoms, this clinical entity escapes the diagnostic consideration of the gynecologist, when women come in with right iliac fossa pain. A case is presented of a 56-year-old woman with a mass in the right small pelvis, which was preoperatively diagnosed as originating from the ovary. An exploratory laparotomy followed in which the uterus and appendages were found to be macroscopically normal, while the mass described above came from the appendix, extended into the anatomical area of the right accessory, and was in contact with the atrophic right ovary. The appendix vermiformis was removed intact. The final pathologic examination confirmed an acellular mucinous tumor of the appendix. Accurate preoperative diagnosis of mucoceles is extremely difficult to make. The formation is discovered in a random imaging test, and the diagnosis is confirmed only intraoperatively.

摘要

阑尾肿瘤通常无症状或伴有轻微、非特异性症状。由于该疾病罕见且缺乏特异性症状,当女性因右下腹疼痛前来就诊时,妇科医生往往不会考虑到这种临床情况。本文介绍了一例56岁女性患者,其右小骨盆有一肿块,术前诊断为起源于卵巢。随后进行了剖腹探查术,术中发现子宫和附件肉眼可见正常,而上述肿块来自阑尾,延伸至右侧附件的解剖区域,并与萎缩的右卵巢接触。完整切除了阑尾。最终病理检查证实为阑尾无细胞黏液性肿瘤。黏液囊肿的术前准确诊断极其困难。该病变是在随机成像检查中发现的,只有在术中才能确诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/ec32096755e8/CRIPA2024-7732249.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/b229aad87316/CRIPA2024-7732249.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/71c48f24bdb6/CRIPA2024-7732249.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/179e1a4e41c5/CRIPA2024-7732249.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/ec32096755e8/CRIPA2024-7732249.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/b229aad87316/CRIPA2024-7732249.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/71c48f24bdb6/CRIPA2024-7732249.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/179e1a4e41c5/CRIPA2024-7732249.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c9/11637618/ec32096755e8/CRIPA2024-7732249.004.jpg

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1
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本文引用的文献

1
Retrospective Review of Outcomes in Non-Invasive Mucinous Appendiceal Neoplasms with and without Peritoneal Spread: A Cohort Study.回顾性分析无腹膜播散和有腹膜播散的非侵袭性黏液性阑尾肿瘤的结果:一项队列研究。
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Epidemiology, histopathology, clinical outcomes and survival of 50 cases of appendiceal mucinous neoplasms: Retrospective cross-sectional single academic tertiary care hospital experience.50例阑尾黏液性肿瘤的流行病学、组织病理学、临床结局及生存情况:单学术三级医疗中心的回顾性横断面研究经验
Ann Med Surg (Lond). 2021 Mar 6;64:102199. doi: 10.1016/j.amsu.2021.102199. eCollection 2021 Apr.
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A Multi-institutional Study of Peritoneal Recurrence Following Resection of Low-grade Appendiceal Mucinous Neoplasms.
低级别阑尾黏液性肿瘤切除术后腹膜复发的多机构研究。
Ann Surg Oncol. 2021 Aug;28(8):4685-4694. doi: 10.1245/s10434-020-09499-y. Epub 2021 Jan 7.
4
Updated staging and patient outcomes in low-grade appendiceal mucinous neoplasms.低级别阑尾黏液性肿瘤的分期更新及患者预后
Mod Pathol. 2021 Jan;34(1):104-115. doi: 10.1038/s41379-020-0628-7. Epub 2020 Jul 29.
5
Clinical Surveillance After Macroscopically Complete Surgery for Low-Grade Appendiceal Mucinous Neoplasms (LAMN) with or Without Limited Peritoneal Spread: Long-Term Results in a Prospective Series.低级别阑尾黏液性肿瘤 (LAMN) 经大体完全切除术后伴或不伴有限腹膜扩散的临床监测:一项前瞻性系列的长期结果。
Ann Surg Oncol. 2018 Apr;25(4):878-884. doi: 10.1245/s10434-018-6341-9. Epub 2017 Dec 21.
6
Strategies for Preventing Pseudomyxoma Peritonei After Resection of a Mucinous Neoplasm of the Appendix.阑尾黏液性肿瘤切除术后预防腹膜假黏液瘤的策略。
Anticancer Res. 2015 Sep;35(9):4943-7.
7
Mucus containing cystic lesions "mucocele" of the appendix: the unresolved issues.阑尾含黏液性囊性病变“黏液囊肿”:未解决的问题。
Int J Surg Oncol. 2015;2015:139461. doi: 10.1155/2015/139461. Epub 2015 Mar 23.
8
Significance of proximal margin involvement in low-grade appendiceal mucinous neoplasms.近端切缘受累在低级别阑尾黏液性肿瘤中的意义。
Arch Pathol Lab Med. 2015 Apr;139(4):518-21. doi: 10.5858/arpa.2014-0246-OA. Epub 2014 Jun 27.
9
Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence.阑尾黏液性肿瘤:116 例临床病理研究并分析复发相关因素。
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10
Prognostic significance of localized extra-appendiceal mucin deposition in appendiceal mucinous neoplasms.阑尾黏液性肿瘤中局部阑尾外黏液沉积的预后意义
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