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保留尿道及背侧包膜开窗的机器人辅助单纯前列腺切除术治疗小前列腺重度下尿路症状:一例报告

Urethra-preserving and dorsal capsule fenestration with robot-assisted simple prostatectomy for severe LUTS in small prostate: a case report.

作者信息

Wen Lijie, Zhang Yue, He Yi, Yu Yang, Yang Bo

机构信息

Department of Urology, The Second Hospital of Dalian Medical University, Dalian, China.

出版信息

Front Surg. 2024 Nov 28;11:1497556. doi: 10.3389/fsurg.2024.1497556. eCollection 2024.

Abstract

BACKGROUND

Small prostates (volume <30 ml) induce bladder outlet obstruction with pathophysiological changes distinct from those associated with large prostates. Treatment options often include transurethral incision of the prostate (TUIP) or transurethral resection of the prostate (TURP). Existing treatments have issues with high recurrence and complication rates. Therefore, we aim to explore a new minimally invasive surgical approach for patients with severe lower urinary tract symptoms (LUTS) and a small prostate.

METHODS

A patient with severe LUTS and a small prostate was admitted to the Department of Urology at the Second Hospital of Dalian Medical University. The patient had no median lobe but presented with multiple bladder stones. Relevant data (IPSS score, urine flow rate, operation time, hemoglobin drop, catheterization time, hospitalization time, residual urine) were collected before and after surgery to assess the safety and efficiency.

RESULTS

The patient was 72 years old with a prostate volume of 22.14 ml, a preoperative IPSS score of 28, PSA of 0.314 ng/ml, maximum urine flow rate of 3.5 ml/s, and a prostate MRI PI-RADS score of 2. The patient underwent robot-assisted cystolithotomy, urethra-preserving prostatectomy and dorsal capsule fenestration. The surgery lasted 105 min, with a postoperative hemoglobin drop of 3 g/L. There was no continuous bladder irrigation postoperatively, and the catheter was removed after 10 days. The patient was hospitalized for 4 days and followed up for 24 months. At 6 months postoperative, the patient had an IPSS score of 6, a QoL score of 1, a urine flow rate of 18 ml/s, and residual urine of 8 ml, with nocturia occurring 1-2 times. At 24 months postoperative, the patient had an IPSS score of 7, a QoL score of 1, a urine flow rate of 21 ml/s, and residual urine of 15 ml, with nocturia occurring 1 time.

CONCLUSION

Robot-assisted urethra-preserving prostatectomy and dorsal capsule fenestration is a promising alternative treatment for patient with severe LUTS due to a small prostate in both long-term safety and efficacy. Further large-sample controlled studies are needed for additional evaluation and validation.

摘要

背景

小前列腺(体积<30 ml)导致膀胱出口梗阻,其病理生理变化与大前列腺相关的变化不同。治疗选择通常包括经尿道前列腺切开术(TUIP)或经尿道前列腺切除术(TURP)。现有治疗方法存在高复发率和并发症发生率的问题。因此,我们旨在探索一种针对严重下尿路症状(LUTS)且前列腺小的患者的新型微创手术方法。

方法

一名患有严重LUTS且前列腺小的患者入住大连医科大学附属第二医院泌尿外科。该患者无中叶,但伴有多发膀胱结石。收集手术前后的相关数据(国际前列腺症状评分[IPSS]、尿流率、手术时间、血红蛋白下降情况、导尿时间、住院时间、残余尿量)以评估安全性和有效性。

结果

患者72岁,前列腺体积为22.14 ml,术前IPSS评分为28分,前列腺特异性抗原(PSA)为0.314 ng/ml,最大尿流率为3.5 ml/s,前列腺磁共振成像前列腺影像报告和数据系统(MRI PI-RADS)评分为2分。患者接受了机器人辅助膀胱结石切除术、保留尿道前列腺切除术和背侧包膜开窗术。手术持续105分钟,术后血红蛋白下降3 g/L。术后无需持续膀胱冲洗,10天后拔除导尿管。患者住院4天,并随访24个月。术后6个月时,患者IPSS评分为6分,生活质量(QoL)评分为1分,尿流率为18 ml/s,残余尿量为8 ml,夜尿1 - 2次。术后24个月时,患者IPSS评分为7分,QoL评分为1分,尿流率为21 ml/s,残余尿量为15 ml,夜尿1次。

结论

机器人辅助保留尿道前列腺切除术和背侧包膜开窗术对于因前列腺小而患有严重LUTS的患者在长期安全性和有效性方面是一种有前景的替代治疗方法。需要进一步的大样本对照研究进行额外评估和验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dfd/11634874/441dde0ada52/fsurg-11-1497556-g001.jpg

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