Agarwal Priyanka, Creanga Adriana D
General Dentist, Harrisburg, Pennsylvania.
Department of Dental Diagnostic Science, Division of Oral and Maxillofacial Radiology, Rutgers School of Dental Medicine, Newark, NJ, USA.
J Oral Maxillofac Pathol. 2024 Jul-Sep;28(3):506-510. doi: 10.4103/jomfp.jomfp_138_23. Epub 2024 Oct 15.
Vascular Leiomyoma of the oral cavity is an uncommon benign soft tissue neoplasia arising from the tunica media of the smooth muscle cells. We reported a rare case of Vascular Leiomyoma involving the retromolar trigone area of a young man. A 24-year-old male presented with a slowly growing mass in the retromolar area, which was associated with pain and difficulty in opening of mouth and eating and drinking. A punch biopsy was taken and sent for histopathological examination which revealed a benign angiomatous lesion. The mass was excised, and the adjoining area was curetted. Histopathological examination confirmed the diagnosis of Vascular Leiomyoma. The immunohistochemistry of cells shows: alpha-smooth muscle (+); vimentin (+), Desmin, actin (+), and S100 (-). Angioleiomyomas are benign lesions, but malignant transformation is a possibility so careful histologic inspection is necessary to distinguish these lesions from their malignant counterpart.
口腔血管平滑肌瘤是一种罕见的良性软组织肿瘤，起源于平滑肌细胞的中膜。我们报告了一例罕见的血管平滑肌瘤病例，累及一名年轻男性的磨牙后三角区。一名24岁男性患者，磨牙后区出现缓慢生长的肿块，伴有疼痛、张口困难及进食饮水困难。进行了切取活检并送去做组织病理学检查，结果显示为良性血管瘤样病变。切除了肿块，并刮除了相邻区域。组织病理学检查确诊为血管平滑肌瘤。细胞免疫组化显示：α-平滑肌（+）；波形蛋白（+），结蛋白、肌动蛋白（+），S100（-）。血管平滑肌瘤是良性病变，但有恶变的可能，因此需要仔细的组织学检查以将这些病变与恶性病变区分开来。
