Nair Shalini, Mahaboob Shahnaz, Mathew Jobin, Thoyakkat Aiswarya
Department of Oral Pathology and Microbiology, PSM College of Dental Science and Research, Thrissur, Kerala, India.
J Oral Maxillofac Pathol. 2024 Jul-Sep;28(3):511-514. doi: 10.4103/jomfp.jomfp_22_24. Epub 2024 Oct 15.
Focal osteoporotic bone marrow defects (FOBMDs) of jaws are rare and usually discovered as an incidental radiographic finding. They present as a poorly demarcated radiolucency affecting the posterior mandible of middle-aged women with pathogenesis remaining unknown. A 60-year-old female patient had visited our dental college for routine dental checkup and oral prophylaxis. Her radiograph revealed a well-defined radiolucency in the left mandibular posterior region as an incidental finding. Clinical examination revealed a diffuse swelling in the above-mentioned region which the patient had not noticed. The patient gave a history of trauma in the same region almost 20 years back. Incisional biopsy was performed. Microscopic examination revealed multiple bits of fatty fibro cellular tissue resembling the bone marrow with aggregates of blood cells. A diagnosis of FOBMD was given. FOBMD, although rare, should be included in differential diagnosis of the radiolucent lesions of the jaws.
颌骨局灶性骨质疏松性骨髓缺损(FOBMDs)较为罕见,通常是在影像学检查时偶然发现。它们表现为界限不清的透射影,累及中年女性的下颌后部,其发病机制尚不清楚。一名60岁女性患者到我们牙科学院进行常规牙科检查和口腔预防。她的X光片显示左下颌后部区域有一个边界清晰的透射影,为偶然发现。临床检查发现上述区域有弥漫性肿胀,患者之前并未注意到。患者自述约20年前在同一区域受过外伤。进行了切开活检。显微镜检查显示有多处类似骨髓的脂肪纤维细胞组织,伴有血细胞聚集。诊断为FOBMD。FOBMD虽然罕见,但在颌骨透射性病变的鉴别诊断中应予以考虑。