Tschernko Edda, Geilen Johannes, Wasserscheid Thomas
Division of Cardiothoracic and Vascular Anesthesia and Intensive Care Medicine, Department of Anesthesiology, General Intensive Care and Pain Medicine, Medical University Vienna, Vienna, Austria.
Curr Opin Anaesthesiol. 2025 Feb 1;38(1):71-79. doi: 10.1097/ACO.0000000000001450. Epub 2024 Dec 16.
Circulatory and respiratory support with extracorporeal membrane oxygenation (ECMO) has gained widespread acceptance during high-end thoracic surgery. The purpose of this review is to summarize the recent knowledge and give an outlook for future developments.
A personalized approach of ECMO use is state of the art for monitoring during surgery. Personalization is increasingly applied during anesthesia for high-end surgery nowadays. This is reflected in the point of care testing (POCT) for anticoagulation and cardiac function during surgery on ECMO combining specific patient data into tailored algorithms. For optimizing protective ventilation MP (mechanical power) is a promising parameter for the future. These personalized methods incorporating numerous patient data are promising for the improvement of morbidity and mortality in high-end thoracic surgery. However, clinical data supporting improvement are not available to date but can be awaited in the future.
Clinical practice during surgery on ECMO is increasingly personalized. The effect of personalization on morbidity and mortality must be examined in the future. Undoubtedly, an increase in knowledge can be expected from this trend towards personalization.
在高端胸外科手术中,体外膜肺氧合(ECMO)的循环和呼吸支持已得到广泛认可。本综述旨在总结近期知识,并展望未来发展。
个性化的ECMO使用方法是手术期间监测的最新技术。如今,个性化在高端手术的麻醉过程中应用越来越广泛。这体现在ECMO手术期间用于抗凝和心脏功能的床旁检测(POCT)中,即将特定患者数据纳入定制算法。为优化保护性通气,机械功率(MP)是未来一个有前景的参数。这些纳入大量患者数据的个性化方法有望改善高端胸外科手术的发病率和死亡率。然而,目前尚无支持改善效果的临床数据,但未来可期。
ECMO手术期间的临床实践越来越个性化。未来必须研究个性化对发病率和死亡率的影响。毫无疑问,这种个性化趋势有望带来知识的增加。