[缺血性心脏线粒体磷脂的脂肪酸组成]
[Fatty acid composition of mitochondrial phospholipids of the ischemic heart].
作者信息
Dagis A I, Toleĭkis A I, Prashkiavichius A K
出版信息
Biull Eksp Biol Med. 1985 Jan;99(1):43-5.
Gas liquid chromatography was used to study fatty acid (FA) composition of lysophosphatidylcholine (lyso-PC) and phosphatidylcholine in isolated rabbit heart mitochondria. In control, lyso-PC and PC were found to contain 95 and 66% of unsaturated FA, respectively. At 1 hour of ischemia (autolysis at 37 degrees C) the percentage of saturated FA in lyso-PC noticeably increased whereas FA composition remained unchanged. It is concluded that changes in FA composition of lyso-PC are caused by phospholipase A2 action.
采用气液色谱法研究离体兔心脏线粒体中溶血磷脂酰胆碱（lyso-PC）和磷脂酰胆碱的脂肪酸（FA）组成。在对照组中，发现lyso-PC和PC分别含有95%和66%的不饱和脂肪酸。在缺血1小时（37℃自溶）时，lyso-PC中饱和脂肪酸的百分比显著增加，而脂肪酸组成保持不变。得出结论：lyso-PC脂肪酸组成的变化是由磷脂酶A2的作用引起的。
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