Lasorsa Francesco, Orsini Angelo, Bignante Gabriele, Biasatti Arianna, Dymanus Kyle A, Feldman-Schultz Oren, Pandolfo Savio Domenico, Setia Shaan, Olweny Ephrem, Cherullo Edward E, Vourganti Srinivas, Autorino Riccardo
Department of Urology, Rush University Medical Center, 1725 W. Harrison Street, Suite 970, Chicago, IL, 60612, USA.
Department of Precision and Regenerative Medicine and Ionian Area-Urology, Andrology and Kidney Transplantation Unit, University of Bari "Aldo Moro", Bari, Italy.
World J Urol. 2024 Dec 13;43(1):30. doi: 10.1007/s00345-024-05391-6.
To evaluate the predictors of delayed discharge for patients undergoing robot-assisted partial nephrectomy (RAPN) at our Institution since the introduction of the single port (SP) robotic system.
We performed a retrospective review of our prospectively maintained database of patients undergoing RAPN from September 2020 to August 2024. Patients were categorized by the postoperative day of their discharge: POD1 (single overnight stay) or POD > 1 (more than one night stay). Multivariable logistic regression analysis was used to test the probability of prolonged hospital stay (defined as more than one night stay) adjusting for age at surgery, surgical approach, Charlson comorbidity index, baseline hemoglobin, antiplatelet or anticoagulant medications, clinical tumor stage, and intraoperative blood transfusion.
Overall, 255 patients were identified for the analysis. Patients discharged on POD1 were younger (p = 0.004), reported a lower Charlson Comorbidity Index (p = 0.002), higher preoperative hemoglobin levels (p = 0.005), and smaller tumor size (p < 0.001). Higher rates of discharge on POD1 were recorded for both multiport transperitoneal (59.5 vs. 40.5%, p = 0.02) and SP retroperitoneal (81.5 vs. 18.5%, p = 0.004). Clinical tumor stage (p = 0.02) and intraoperative blood transfusion (p = 0.05) emerged as independent risk factors for POD > 1. Baseline hemoglobin emerged as a protective factor (p = 0.05) as well as SP approach (p = 0.03).
SP-RAPN holds potential to shorten hospitalization without hampering surgical outcomes. By maximizing the adoption of a RP approach and minimizing surgical invasiveness, SP robotic surgery allows to significantly expand the pool of RAPN patients that can be discharged after a single overnight stay.
评估自引入单孔(SP)机器人系统以来,在本机构接受机器人辅助部分肾切除术(RAPN)的患者延迟出院的预测因素。
我们对2020年9月至2024年8月期间接受RAPN的患者的前瞻性维护数据库进行了回顾性分析。根据患者出院的术后天数进行分类:术后第1天出院(单次过夜住院)或术后第1天之后出院(住院超过一晚)。采用多变量逻辑回归分析来测试延长住院时间(定义为住院超过一晚)的概率,并对手术年龄、手术方式、查尔森合并症指数、基线血红蛋白、抗血小板或抗凝药物、临床肿瘤分期和术中输血情况进行校正。
总体而言,共纳入255例患者进行分析。术后第1天出院的患者更年轻(p = 0.004),查尔森合并症指数更低(p = 0.002),术前血红蛋白水平更高(p = 0.005),肿瘤体积更小(p < 0.001)。多端口经腹手术(59.5%对40.5%,p = 0.02)和SP后腹腔镜手术(81.5%对18.5%,p = 0.004)术后第1天出院的比例更高。临床肿瘤分期(p = 0.02)和术中输血(p = 0.05)是术后第1天之后出院的独立危险因素。基线血红蛋白是一个保护因素(p = 0.05),SP手术方式也是(p = 0.03)。
SP-RAPN有缩短住院时间而不影响手术效果的潜力。通过最大限度地采用机器人手术方式并最小化手术侵袭性,SP机器人手术能够显著扩大可在单次过夜住院后出院的RAPN患者群体。