Cannon S R, Sweetnam D R
Cancer. 1985 Feb 15;55(4):836-40. doi: 10.1002/1097-0142(19850215)55:4<836::aid-cncr2820550421>3.0.co;2-f.
The relationship between dyschondroplasia (Ollier's Disease) and the possibility of malignant change is well known. The authors describe a patient who developed four primary chondrosarcomas over 11 years. These were treated by local wide excision and, in two sites, prosthetic replacement to preserve the limb. To the authors' knowledge, no patient with more than two primary chondrosarcomas has previously been described.
软骨发育异常(Ollier病)与恶变可能性之间的关系是众所周知的。作者描述了一名在11年期间发生4例原发性软骨肉瘤的患者。这些病例采用局部广泛切除治疗,在两个部位进行了假体置换以保留肢体。据作者所知,此前尚未有超过2例原发性软骨肉瘤患者的报道。