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根据蝶鞍区肿瘤的形态和生长方向进行诊断的考量

Diagnostic considerations of tumors of the sellar region according to their geometry and vector growth.

作者信息

Ortiz Machín Marlon Manuel, López Arbolay Omar, Vargas Gálvez Carlos Roberto

机构信息

Servicio de Neurocirugía, Hospital "Hermanos Ameijeiras", La Habana, Cuba.

Servicio de Neurocirugía, Hospital "Hermanos Ameijeiras", La Habana, Cuba.

出版信息

Neurocirugia (Engl Ed). 2025 May-Jun;36(3):179-184. doi: 10.1016/j.neucie.2024.12.003. Epub 2024 Dec 12.

DOI:10.1016/j.neucie.2024.12.003
PMID:39672469
Abstract

INTRODUCTION

Sellar and parasellar tumors are frequent lesions in neurosurgical practice, highlighting pituitary adenomas, craniopharyngiomas, and sellar tubercle meningiomas. The clinical manifestations are similar, however; There are imaging aspects that differentiate them.

OBJECTIVE

Show imaging aspects of tumors in the sellar and parasellar region that guide their histopathological diagnosis.

METHOD

A descriptive, longitudinal and prospective study was carried out that included 200 patients from the Hermanos Ameijeiras Hospital, of which 120 had a histopathological diagnosis of pituitary adenoma, 50 of craniopharyngioma and 30 of sellar tubercle meningioma. The variations in the displacement of the point of the anterior communicating arterial complex and in the premammillary angle were analyzed by means of a cerebral nuclear magnetic resonance study. For data analysis, absolute and relative frequencies were used as summary measures.

RESULTS

A cephalic displacement of the anterior communicating arterial complex was evident in the craniopharyngiomas, of 10-11.9 mm (84.0 %); in pituitary macroadenomas, 12-14 mm (78.3%); and in sellar tubercle meningioma, ≥14 (86.6 %) mm. When evaluating the premammillary angle, pituitary adenomas were identified between 85º and 95º (73.3 %); in craniopharyngiomas, <85º (90.0 %); and in meningiomas of the sellar tubercle, between 85 and 95º (86.6 %).

CONCLUSIONS

The present study allows us to identify imaging characteristics in sellar and parasellar tumors that guide with high certainty the histopathological diagnosis and thus establish a more effective treatment.

摘要

引言

鞍区和鞍旁肿瘤是神经外科常见病变,其中垂体腺瘤、颅咽管瘤和鞍结节脑膜瘤较为突出。然而,它们的临床表现相似;在影像学方面存在差异可将它们区分开来。

目的

展示鞍区和鞍旁区域肿瘤的影像学特征,以指导其组织病理学诊断。

方法

开展了一项描述性、纵向和前瞻性研究,纳入了200名来自阿梅耶拉斯兄弟医院的患者,其中120例经组织病理学诊断为垂体腺瘤,50例为颅咽管瘤,30例为鞍结节脑膜瘤。通过脑核磁共振研究分析前交通动脉复合体点的移位和乳头前角的变化。数据分析采用绝对频率和相对频率作为汇总指标。

结果

颅咽管瘤中前交通动脉复合体明显向头侧移位,为10 - 11.9毫米(84.0%);垂体大腺瘤中为12 - 14毫米(78.3%);鞍结节脑膜瘤中≥14毫米(86.6%)。评估乳头前角时,垂体腺瘤在85°至95°之间(73.3%);颅咽管瘤中<85°(90.0%);鞍结节脑膜瘤在85°至95°之间(86.6%)。

结论

本研究使我们能够识别鞍区和鞍旁肿瘤的影像学特征,这些特征能高度准确地指导组织病理学诊断,从而制定更有效的治疗方案。

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