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开放椎板切除术加后外侧融合术与开放椎板切除术加经椎间孔腰椎椎间融合术治疗L4-L5节段退变融合的手术方法:一项比较性有限元研究

Open laminectomy plus posterolateral fusion versus open laminectomy plus transforaminal lumbar interbody fusion surgical approaches for fusing degenerated L4-L5 segment: A comparative finite element study.

作者信息

Pradeep Kishore, Pal Bidyut

机构信息

Department of Mechanical Engineering, Indian Institute of Engineering Science and Technology (IIEST), Shibpur, Howrah 711103, West Bengal, India.

出版信息

Med Eng Phys. 2024 Dec;134:104261. doi: 10.1016/j.medengphy.2024.104261. Epub 2024 Nov 19.

DOI:10.1016/j.medengphy.2024.104261
PMID:39672661
Abstract

Various finite element (FE) studies reported the biomechanical effects of fusion surgeries in the lumbar spine. However, a comparative study on Open laminectomy plus Posterolateral Fusion (OL-PLF) and Open Laminectomy plus Transforaminal Lumbar Interbody Fusion (OL-TLIF) for fusing an L4-L5 segment has not been reported in the literature. The present comparative FE study evaluates the biomechanical variations in an L4-L5 segment fused using OL-PLF and OL-TLIF surgical approaches. The three-dimensional implanted models were constructed from a computed-tomography scan dataset using image processing software. The models were simulated for the physiological movements such as lateral bending, flexion and extension. The OL-TLIF model had a considerably larger peak equivalent strain than the OL-PLF model under extension (126 %), lateral bending (88 %) and flexion (13 %). However, in both implanted models, a peak equivalent strain above the compressive yield strain limit of the vertebra (0.007) was observed over 60 % of the L4-L5 fused segment, indicating an imminent post-operative bone failure under the imposed loading conditions. The maximum equivalent strain observed in the disc and endplates of the L3-L4 segment was substantially larger to initiate the adjacent segment degeneration. No discernible biomechanical benefits were observed for the OL-TLIF or OL-PLF approaches in fusing the L4-L5 segment.

摘要

多项有限元(FE)研究报告了腰椎融合手术的生物力学效应。然而,文献中尚未报道关于开放椎板切除术加后外侧融合术(OL-PLF)和开放椎板切除术加经椎间孔腰椎椎间融合术(OL-TLIF)融合L4-L5节段的比较研究。本比较性有限元研究评估了采用OL-PLF和OL-TLIF手术方法融合L4-L5节段时的生物力学变化。使用图像处理软件从计算机断层扫描数据集构建三维植入模型。对模型进行了诸如侧弯、前屈和后伸等生理运动的模拟。在伸展(126%)、侧弯(88%)和前屈(13%)时,OL-TLIF模型的峰值等效应变比OL-PLF模型大得多。然而,在两个植入模型中,在L4-L5融合节段的60%以上观察到峰值等效应变超过椎体的压缩屈服应变极限(0.007),表明在施加的加载条件下术后骨即将失效。在L3-L4节段的椎间盘和终板中观察到的最大等效应变明显更大,从而引发相邻节段退变。在融合L4-L5节段时,未观察到OL-TLIF或OL-PLF方法有明显的生物力学优势。

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引用本文的文献

1
Transforaminal lumbar interbody fusion (TLIF) surgery: A finite element analysis of open and minimally invasive approach on L4-L5 segment.经椎间孔腰椎椎体间融合术(TLIF)手术:L4-L5节段开放与微创入路的有限元分析
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