Venter Carina, Tan William, Pickett-Nairne Kaci, Amara Shriya, Venter Manzi, Glueck Deborah H, Boden Stina, Comotti Anna, Wang Laura
Section of Pediatric Allergy and Immunology, University of Colorado, Children's Hospital Colorado, Denver, Colorado, USA.
University of Cambridge, Cambridge, UK.
Pediatr Allergy Immunol. 2024 Dec;35(12):e70016. doi: 10.1111/pai.70016.
Allergic diseases including food allergy, atopic dermatitis, asthma, and allergic rhinitis are increasing. Nutritional intake may play a role in this increase. Systematic reviews indicate that intake of specific nutrients and foods does not prevent allergic diseases. The role of the overall diet as measured by dietary patterns (Diet diversity, Dietary inflammatory index, Mediterranean diet score, Healthy eating index, Maternal diet index, ultra-processed food dietary patterns, and others) have not been systematically reviewed. We aim to investigate the association between overall maternal dietary intake during pregnancy and offspring allergy outcomes. The following databases will be searched: PubMed, OVID Medline, Web of Science, and Embase. Studies with publication dates up to November 28, 2024, will be eligible. We will perform our last search on November 28, 2024. There will be no restrictions by geographical location but only studies published in English will be included. Risk of bias in the included studies will be assessed using the ROBINS-I Cochrane assessment tool. Data will be discussed and narratively, and studies that present comparable data will be used in meta-analyses with a random effects model. Data will be discussed and narratively, and studies that present comparable data will be used in meta-analyses with a random effects model. The results of this systematic review and meta-analysis will be published in a peer-reviewed journal. Systematic reviews provide methodology for objective evidence synthesis. The systematic review will provide useful information regarding the role of maternal dietary patterns during pregnancy and their association with offspring allergy outcomes.
包括食物过敏、特应性皮炎、哮喘和过敏性鼻炎在内的过敏性疾病正在增加。营养摄入可能在这种增加中起作用。系统评价表明，特定营养素和食物的摄入并不能预防过敏性疾病。通过饮食模式（饮食多样性、饮食炎症指数、地中海饮食评分、健康饮食指数、孕产妇饮食指数、超加工食品饮食模式等）衡量的总体饮食的作用尚未得到系统评价。我们旨在研究孕期母亲总体饮食摄入与后代过敏结局之间的关联。将检索以下数据库：PubMed、OVID Medline、Web of Science和Embase。截至2024年11月28日发表的研究将符合条件。我们将于2024年11月28日进行最后一次检索。不受地理位置限制，但仅纳入以英文发表的研究。将使用ROBINS-I Cochrane评估工具评估纳入研究的偏倚风险。数据将进行叙述性讨论，呈现可比数据的研究将用于随机效应模型的荟萃分析。数据将进行叙述性讨论，呈现可比数据的研究将用于随机效应模型的荟萃分析。本系统评价和荟萃分析的结果将发表在同行评审期刊上。系统评价为客观证据综合提供了方法。该系统评价将提供有关孕期母亲饮食模式的作用及其与后代过敏结局的关联的有用信息。
