科特斯洛辛D，一种源自海绵真菌的新型环五肽2 - 18。
Cotteslosin D, a new cyclopentapeptide from a sponge-derived fungus 2-18.
作者信息
Zheng Maokun, Huang Zheng, Zheng Yanxiu, Tang Yukun, Wang Jun, Yang Shengpu
机构信息
Shandong Provincial Institute of Pharmaceutical Research, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
出版信息
Nat Prod Res. 2024 Dec 14:1-6. doi: 10.1080/14786419.2024.2441495.
A new cyclopentapeptide, cotteslosin D (), was isolated from the cultures of a sponge-derived fungus 2-18. The structure of was eluvidated as -(-Me-L-Tyr-L-Val-L-Pro-L-Tyr-L-Phe) on the basis of extensive spectroscopic analysis and chemical methods. Compound displayed weak antibacterial activities against and .
一种新的环五肽，棉子糖素D（），从一种海绵来源真菌2-18的培养物中分离得到。基于广泛的光谱分析和化学方法，其结构被确认为-（-甲基-L-酪氨酸-L-缬氨酸-L-脯氨酸-L-酪氨酸-L-苯丙氨酸）。化合物对和显示出较弱的抗菌活性。
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