Ripoll Juan G, Chang Marvin G, Bittner Edward A, Ortoleva Jamel, Khromava Maryna, Bradley Derek T, Griffin Emily K, Diaz Soto Juan C, Wieruszewski Patrick M, Chang Kitae, Nabzdyk Christoph S, Ramakrishna Harish
Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN.
Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA.
J Cardiothorac Vasc Anesth. 2025 Mar;39(3):818-835. doi: 10.1053/j.jvca.2024.11.020. Epub 2024 Nov 26.
The 2024 European Society of Cardiology guidelines for atrial fibrillation (AF) emphasize a patient-centered approach to management, structured around the AF-CARE pathway: Comorbidity and risk factor management (C), Avoiding stroke and thromboembolism (A), Reducing symptoms through rate and rhythm control (R), and Evaluation and dynamic reassessment (E). This framework ensures that comorbidities such as hypertension, heart failure, diabetes, and obesity are effectively managed to prevent disease progression and improve outcomes. A key principle of the guidelines is shared decision making involving patients, families, caregivers, and healthcare teams to ensure individualized care that reflects patient preferences. The guidelines also stress healthcare equity, advocating for the elimination of disparities related to sex, ethnicity, disability, and socioeconomic status. For diagnosis, electrocardiographic confirmation of clinical AF is essential, followed by risk stratification using the CHA₂DS₂-VASc score to guide anticoagulation therapy. Direct oral anticoagulants are preferred for most patients because of their good safety profile. Stroke prevention is prioritized, with rhythm control as first-line treatment for suitable patients. For those with persistent symptoms despite medications, catheter ablation is recommended. Rate control strategies, including beta-blockers, digoxin, and calcium channel blockers, are used to manage heart rate and symptoms. Ongoing education for patients, families, and providers supports informed decision making and dynamic reassessment, optimizing patient outcomes and quality of life.
2024年欧洲心脏病学会心房颤动(AF)指南强调以患者为中心的管理方法,围绕AF-CARE路径构建:合并症和危险因素管理(C)、预防中风和血栓栓塞(A)、通过心率和节律控制减轻症状(R)以及评估和动态重新评估(E)。该框架确保有效管理高血压、心力衰竭、糖尿病和肥胖等合并症,以防止疾病进展并改善预后。指南的一项关键原则是患者、家属、护理人员和医疗团队共同参与决策,以确保提供反映患者偏好的个性化护理。指南还强调医疗公平,主张消除与性别、种族、残疾和社会经济地位相关的差异。对于诊断,临床房颤的心电图确认至关重要,随后使用CHA₂DS₂-VASc评分进行风险分层,以指导抗凝治疗。由于安全性良好,大多数患者首选直接口服抗凝剂。预防中风是首要任务,对于合适的患者,节律控制作为一线治疗。对于尽管用药仍有持续症状的患者,建议进行导管消融。包括β受体阻滞剂、地高辛和钙通道阻滞剂在内的心率控制策略用于管理心率和症状。对患者、家属和医疗服务提供者的持续教育支持明智决策和动态重新评估,优化患者预后和生活质量。