Clúa Joaquín, Jaskolowski Aime, Abriata Luciano A, Poirier Yves
Department of Plant Molecular Biology, Biophore Building, University of Lausanne, 1015 Lausanne, Switzerland.
Department of Plant Molecular Biology, Biophore Building, University of Lausanne, 1015 Lausanne, Switzerland.
Trends Plant Sci. 2025 Jun;30(6):665-677. doi: 10.1016/j.tplants.2024.11.007. Epub 2024 Dec 13.
Biotic and abiotic stresses constrain plant growth worldwide. Therefore, understanding the molecular mechanisms contributing to plant resilience is key to achieving food security. In recent years, proteins containing dopamine β-monooxygenase N-terminal (DOMON) and/or cytochrome b561 domains have been identified as important regulators of plant responses to multiple stress factors. Recent findings show that these proteins control the redox states of different cellular compartments to modulate plant development, stress responses, and iron homeostasis. In this review, we analyze the distribution and structure of proteins with DOMON and/or cytochrome b561 domains in model plants. We also discuss their biological roles and the molecular mechanisms by which this poorly characterized group of proteins exert their functions.
生物和非生物胁迫限制了全球范围内的植物生长。因此，了解植物恢复力的分子机制是实现粮食安全的关键。近年来，含有多巴胺β-单加氧酶N端（DOMON）和/或细胞色素b561结构域的蛋白质已被确定为植物对多种胁迫因子响应的重要调节因子。最近的研究结果表明，这些蛋白质控制不同细胞区室的氧化还原状态，以调节植物发育、胁迫响应和铁稳态。在本综述中，我们分析了模式植物中具有DOMON和/或细胞色素b561结构域的蛋白质的分布和结构。我们还讨论了它们的生物学作用以及这组特征尚不明确的蛋白质发挥功能的分子机制。
