Zhang Li, Yan Hui-Feng
Department of Comprehensive Interventional, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College (Jiangxi Provincial Key Laboratory of Intelligent Medical Imaging), Nanchang University, Nanchang 330006, Jiangxi Province, China.
World J Diabetes. 2024 Dec 15;15(12):2293-2301. doi: 10.4239/wjd.v15.i12.2293.
Individuals with diabetes mellitus have a higher risk of developing malignant tumors, and diagnosing these tumors can be challenging.
To confirm the benefits of using peripherally inserted central catheters (PICCs) in contrast-enhanced computerized tomography (CECT) for diagnostic imaging in diabetic patients with malignant tumors and to provide a research basis for follow-up research.
This retrospective study analyzed 204 diabetic patients with malignancies treated at The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, from January 2024 to June 2024. The patients were divided into two groups: A control group ( = 102) with indwelling peripheral intravenous catheters and a research group ( = 102) with high-pressure-resistant PICC. The study compared baseline data, the incidence of iodine contrast extravasation during CECT, the incidence of adverse events (discomfort, redness and swelling at the puncture site, and blood oozing), imaging quality, nursing time, intubation success rate, number of venipuncture attempts, and catheter maintenance cost.
Male patients accounted for 51.96% in the control group and 55.88% in the research group; the average age was (59.68 ± 11.82) years in the control group and (61.41 ± 12.92) years in the research group; the proportions of lung cancer, colorectal cancer, and gastric cancer patients in the control group were 42.16%, 38.24%, and 19.61%, respectively, while those in the research group were 34.31%, 37.25%, and 28.43%, respectively. Except for the gender distribution, age, and cancer type mentioned above, other general information such as underlying diseases, puncture location, and long-term chemotherapy shows no significant differences as tested ( > 0.05). The results showed that the research group had significantly reduced incidence of iodine contrast extravasation (7 1, = 0.031), similar incidence of adverse events (11 7, = 0.324), reduced nursing time [(18.50 ± 2.68) minutes (13.26 ± 3.00) minutes, = 0.000], fewer venipuncture attempts [(2.21 ± 0.78) times (1.49 ± 0.58) times, = 0.000], lower catheter maintenance cost [(1251.79 ± 205.47) China yuan (CNY) (1019.25 ± 117.28) CNY, = 0.000], increased intubation success rate (16.67% 58.82%, = 0.000), and better imaging quality (85.29% 94.12%, = 0.038).
High-pressure-resistant PICCs can lessen the physical burden of diabetic patients during nursing, reduce treatment costs, and improve the efficiency and quality of imaging for diagnosis malignant tumors.
糖尿病患者发生恶性肿瘤的风险较高，且这些肿瘤的诊断具有挑战性。
确认在糖尿病合并恶性肿瘤患者的诊断性成像中，使用经外周静脉穿刺中心静脉导管（PICC）行增强计算机断层扫描（CECT）的益处，并为后续研究提供研究依据。
本回顾性研究分析了2024年1月至2024年6月在南昌大学江西医学院第二附属医院接受治疗的204例糖尿病合并恶性肿瘤患者。患者分为两组：对照组（n = 102）采用外周静脉留置导管，研究组（n = 102）采用耐高压PICC。本研究比较了基线数据、CECT期间碘造影剂外渗的发生率、不良事件（不适、穿刺部位红肿及渗血）的发生率、成像质量、护理时间、置管成功率、静脉穿刺尝试次数以及导管维护成本。
对照组男性患者占51.96%，研究组占55.88%；对照组平均年龄为（59.68±11.82）岁，研究组为（61.41±12.92）岁；对照组肺癌、结直肠癌和胃癌患者的比例分别为42.16%、38.24%和19.61%，而研究组分别为34.31%、37.25%和28.43%。除上述性别分布、年龄和癌症类型外，其他一般信息如基础疾病、穿刺部位和长期化疗等经检验差异无统计学意义（P>0.05）。结果显示，研究组碘造影剂外渗发生率显著降低（7 vs 1，P = 0.031），不良事件发生率相近（11 vs 7，P = 0.324），护理时间缩短[（18.50±2.68）分钟 vs （13.26±3.00）分钟，P = 0.000]，静脉穿刺尝试次数减少[（2.21±0.78）次 vs （1.49±0.58）次，P = 0.000]，导管维护成本降低[（1251.79±205.47）元人民币（CNY）vs （1019.25±117.28）CNY，P = 0.000]，置管成功率提高（16.67% vs 58.82%，P = 0.000），成像质量更好（85.29% vs 94.12%，P = 0.038）。
耐高压PICC可减轻糖尿病患者护理期间的身体负担，降低治疗成本，并提高恶性肿瘤诊断成像的效率和质量。
