急性高血压打开血脑屏障后兔脑的水和电解质含量
Water and electrolyte content of rabbit brain after opening the blood-brain barrier by acute hypertension.
作者信息
Ziylan Y Z, Gökhan N
出版信息
Exp Neurol. 1985 Feb;87(2):198-205. doi: 10.1016/0014-4886(85)90210-9.
Changes in water and electrolyte content of the brain and edema formation after acute, drug-induced hypertension were studied in albino rabbits. Blood-brain and blood-cerebrospinal fluid (CSF) barriers opened to Evans blue-albumin when systemic blood pressure was elevated abruptly to more than 160 mm Hg by i.v. injection of Aramin. No statistically significant changes in sodium and potassium content of brain, muscle, and CSF were observed. Measurable brain edema did not develop. The results suggest that short-lasting hypertensive barrier opening does not cause brain edema, but may enhance a tendency for brain edema.
对白化兔急性药物性高血压后大脑水和电解质含量的变化以及脑水肿形成进行了研究。通过静脉注射阿拉明将全身血压突然升高至160毫米汞柱以上时，血脑屏障和血脑脊液（CSF）屏障对伊文思蓝 - 白蛋白开放。未观察到大脑、肌肉和脑脊液中钠和钾含量有统计学意义的变化。未出现可测量的脑水肿。结果表明，短暂的高血压性屏障开放不会引起脑水肿，但可能会增强脑水肿的倾向。
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