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包含透明细胞癌和子宫内膜样癌的混合性卵巢癌：病例报告

Mixed Ovarian Carcinoma Comprising Clear Cell Carcinoma and Endometrioid Carcinoma: A Case Report.

作者信息

Susanto Jason D, Hendrieta Nelwan Praisela S, Gultom Fajar L, Sirait Batara I, Effendi Iwan K

机构信息

General Medicine, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta, IDN.

Obstetrics and Gynecology, Universitas Kristen Indonesia General Hospital, Jakarta, IDN.

出版信息

Cureus. 2024 Nov 11;16(11):e73483. doi: 10.7759/cureus.73483. eCollection 2024 Nov.

DOI:10.7759/cureus.73483
PMID:39677071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11638022/
Abstract

We present a unique case of mixed ovarian carcinoma, including both clear cell carcinoma (CCC) and grade 1 endometrioid carcinoma (EC) in a 49-year-old woman. The patient had no complaints of pain but presented with an enlarged abdomen, necessitating a thorough diagnostic assessment. Histopathological evaluation revealed an unusual histological juxtaposition of CCC coexisting with grade 1 EC found in an ovarian mass, resulting in diagnostic and therapeutic challenges. A comprehensive approach was used to treat this particular case of mixed ovarian cancer, which included surgical procedures and adjuvant treatments. This case emphasizes the significance of identifying and assessing mixed ovarian carcinomas in order to develop customized treatment plans, as well as the necessity of further research into the basic underlying causes of such unusual presentations.

摘要

我们报告了一例独特的混合性卵巢癌病例，患者为一名49岁女性，其卵巢癌包含透明细胞癌（CCC）和1级子宫内膜样癌（EC）。患者无疼痛主诉，但出现腹部增大，因此需要进行全面的诊断评估。组织病理学评估显示，在一个卵巢肿块中发现CCC与1级EC存在异常的组织学并列，这带来了诊断和治疗上的挑战。针对这例特殊的混合性卵巢癌采用了综合治疗方法，包括手术和辅助治疗。该病例强调了识别和评估混合性卵巢癌以制定个性化治疗方案的重要性，以及进一步研究此类异常表现根本原因的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/90eb0a6d2100/cureus-0016-00000073483-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/aac2b034efad/cureus-0016-00000073483-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/454b28f97bd4/cureus-0016-00000073483-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/66f0ab830006/cureus-0016-00000073483-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/2beef1c97874/cureus-0016-00000073483-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/90eb0a6d2100/cureus-0016-00000073483-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/aac2b034efad/cureus-0016-00000073483-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/454b28f97bd4/cureus-0016-00000073483-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/66f0ab830006/cureus-0016-00000073483-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/2beef1c97874/cureus-0016-00000073483-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1683/11638022/90eb0a6d2100/cureus-0016-00000073483-i05.jpg

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本文引用的文献

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Prz Menopauzalny. 2023 Jun;22(2):93-104. doi: 10.5114/pm.2023.128661. Epub 2023 Jun 14.
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Advanced Stage Clear Cell Ovarian Carcinoma Mimicking Uterine Sarcoma Without Gross Residual Tumor During Primary Surgery: A Case Report.
原发性手术时无肉眼可见残留肿瘤的晚期透明细胞卵巢癌酷似子宫肉瘤：一例报告
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The proteome of clear cell ovarian carcinoma.透明细胞卵巢癌的蛋白质组。
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Ovarian endometrioid carcinoma and clear cell carcinoma: A 21-year retrospective study.卵巢子宫内膜样癌和透明细胞癌：一项 21 年回顾性研究。
J Ovarian Res. 2021 May 4;14(1):63. doi: 10.1186/s13048-021-00804-1.
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Int J Cancer. 2020 Oct 15;147(8):2121-2130. doi: 10.1002/ijc.33012. Epub 2020 Apr 25.
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