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伴有髂腰肌脓肿的骶髂关节结核:诊断与治疗挑战的病例报告

Sacroiliac Joint Tuberculosis With Concomitant Iliopsoas Abscess Suggesting a Diagnostic and Therapeutic Challenge: A Case Report.

作者信息

Symeonidou Elissavet, Fouza Ariadni, Molyvas Dimitrios, Pyrpasopoulou Athina, Arapoglou Stergios, SidiropouIou Maria S, Gouta Chrysoula, Gianna Kalliopi, Deligiorgi Sofia, Marneri Alexandra, Nakou Chrysoula, Massa Eleni, Mouloudi Eleni, Mpallas Konstantinos

机构信息

5th Department of Surgery, Ippokrateio General Hospital/Aristotle University of Thessaloniki, Thessaloniki, GRC.

2nd Propaedeutic Department of Internal Medicine, Ippokrateio General Hospital of Thessaloniki, Thessaloniki, GRC.

出版信息

Cureus. 2024 Nov 14;16(11):e73674. doi: 10.7759/cureus.73674. eCollection 2024 Nov.

Abstract

Sacroiliac joint (SIJ) tuberculosis (TB) is an infrequent clinical entity, especially in developed countries. The symptoms are usually non-specific, and therefore it may mimic a variety of degenerative and non-degenerative diseases, hampering the diagnosis. An interesting case of SIJ infection with psoas abscess in a 77-year-old male is presented in the current article. The patient presented to the Infectious Diseases Clinic complaining of prolonged fever and difficulty walking. The fever was intermittent, it appeared usually at night, and it reached up to 39 degrees Celsius and was accompanied by chills. Magnetic resonance imaging (MRI) indicated SIJ osteomyelitis accompanied by two iliopsoas abscesses above the joint. Computed tomography (CT)-guided aspiration of the abscess was performed twice, but the microbiological culture did not grow any pathogens; Gene-X-Pert performed on the drained pus was negative. An open biopsy with drainage of the abscess cavities and bone biopsy was performed and set the diagnosis, and the anti-TB treatment was initiated. Shortly after the surgical procedure, the patient developed confusion and relapse of high-grade fever, and tubercular meningoencephalitis was diagnosed following an MRI of the brain, which revealed compatible lesions. The patient was intubated and transferred to the intensive care unit (ICU). A quadruple anti-TB regimen was administered. However, the patient's condition deteriorated as he developed necrosis in the cortex and basal ganglia and the outcome was fatal. This article aims to raise awareness regarding this rare clinical entity, whose diagnostic and therapeutic management is particularly demanding.

摘要

骶髂关节结核是一种罕见的临床病症,在发达国家尤为少见。其症状通常不具有特异性,因此可能会与多种退行性和非退行性疾病相似,从而妨碍诊断。本文介绍了一例77岁男性骶髂关节感染合并腰大肌脓肿的有趣病例。该患者前往传染病诊所就诊,主诉长期发热和行走困难。发热呈间歇性,通常在夜间出现,体温高达39摄氏度,并伴有寒战。磁共振成像(MRI)显示骶髂关节骨髓炎,并伴有关节上方的两个髂腰肌脓肿。在计算机断层扫描(CT)引导下对脓肿进行了两次穿刺抽吸,但微生物培养未培养出任何病原体;对引流脓液进行的Gene-X-Pert检测结果为阴性。进行了脓肿腔引流和骨活检的开放性活检以明确诊断,并开始抗结核治疗。手术后不久,患者出现意识模糊和高热复发,脑部MRI检查后诊断为结核性脑膜脑炎,显示出符合的病变。患者被插管并转入重症监护病房(ICU)。给予了四联抗结核治疗方案。然而,患者的病情恶化,出现了皮质和基底节坏死,最终死亡。本文旨在提高对这种罕见临床病症的认识,其诊断和治疗管理极具挑战性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c768/11645855/2128de04975b/cureus-0016-00000073674-i01.jpg

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