Kumar Mithilesh, Priya Neha, Kumar Abhay, Kujur Anit, Kachhap Atul, Sagar Vidya, Karn Ajit K, Narain Smiti
Community Medicine, Rajendra Institute of Medical Sciences, Ranchi, IND.
General Medicine, Rajendra Institute of Medical Sciences, Ranchi, IND.
Cureus. 2024 Nov 13;16(11):e73636. doi: 10.7759/cureus.73636. eCollection 2024 Nov.
Adherence to antiretroviral therapy (ART) is the most important factor in the management of human immunodeficiency virus (HIV). This study examines the level of nonadherence to ART and the predictors of interventions to improve ART adherence in Jharkhand, a state with a predominance of tribes.
The present study was conducted at the ART center, Rajendra Institute of Medical Sciences (RIMS), Ranchi, Jharkhand. As it represents most patients from the state and was easily accessible to us, this center was taken as the study site. Considering ART intake, 30 tribal and 30 non-tribal patients were selected. All patients' baseline data was taken from the center and follow-up visits were done at their homes. Information regarding sociodemographic profile, ART regimen, adherence to ART, and reasons for nonadherence was collected. The interviews were recorded on audiotape, transcribed, and translated verbatim. We used a thematic approach to analyze the data.
In our study, the prevalence of ART at the RIMS ART center was 21.7%, and the causes of non-adherence were asked in depth. The most common reason for nonadherence to treatment was the traveling distance and cost incurred in travel.
Comprehensive research can provide valuable insights into the reasons behind nonadherence and help develop targeted interventions to promote adherence. Some incentives can be provided along with treatment to cover long-distance travel expenses and loss of wages. Delivery of drugs to ART centers can be more regularized.
坚持抗逆转录病毒疗法(ART)是人类免疫缺陷病毒(HIV)管理中最重要的因素。本研究调查了印度恰尔肯德邦(一个部落占主导的邦)抗逆转录病毒疗法的不依从水平以及改善抗逆转录病毒疗法依从性干预措施的预测因素。
本研究在恰尔肯德邦兰契市的拉金德拉医学科学研究所(RIMS)的抗逆转录病毒疗法中心进行。由于该中心代表了该邦的大多数患者且我们很容易到达,所以选取该中心作为研究地点。考虑到抗逆转录病毒疗法的治疗情况,选取了30名部落患者和30名非部落患者。所有患者的基线数据均取自该中心,并在他们家中进行随访。收集了有关社会人口学特征、抗逆转录病毒疗法方案、抗逆转录病毒疗法依从性以及不依从原因的信息。访谈内容录在录音带上,转录并逐字翻译。我们采用主题分析法对数据进行分析。
在我们的研究中,RIMS抗逆转录病毒疗法中心的抗逆转录病毒疗法普及率为21.7%,并深入询问了不依从的原因。不坚持治疗的最常见原因是出行距离和出行费用。
全面的研究可以为不依从背后的原因提供有价值的见解,并有助于制定有针对性的干预措施以促进依从性。可以在治疗的同时提供一些激励措施,以支付长途旅行费用和工资损失。向抗逆转录病毒疗法中心运送药物可以更加规范。