Keller F, Wagner K, Lenz T, Pommer W, Hahn G, Molzahn M, Krause P H
Gut. 1985 Feb;26(2):208-11. doi: 10.1136/gut.26.2.208.
We report two patients with hepatorenal syndrome who recovered from oliguria and renal failure after temporary treatment with haemodialysis. Hepatorenal syndrome developed under diuretic treatment in both patients. Volume expansion, dopamine, and prostaglandin I2 did not improve renal function. In the one patient with alcoholic cirrhosis, renal biopsy showed only minimal alterations of glomeruli, tubuli, and arterial vessels. In the other case, the deterioration and improvement in renal function parallelled changes in acute alcohol-toxic hepatic function. We conclude that haemodialysis should be considered for treatment of hepatorenal syndrome in selected patients where reversal of liver failure can be expected.
我们报告了两名肝肾综合征患者，他们在接受临时血液透析治疗后，少尿和肾衰竭症状得到缓解。两名患者均在利尿治疗过程中发生了肝肾综合征。扩容、多巴胺和前列腺素I2均未能改善肾功能。其中一名酒精性肝硬化患者的肾活检显示肾小球、肾小管和动脉血管仅有轻微改变。在另一例患者中，肾功能的恶化和改善与急性酒精性肝损伤的变化平行。我们得出结论，对于预期肝功能可逆转的部分患者，应考虑采用血液透析治疗肝肾综合征。
