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透明质酸钠关节腔内注射联合持续康复护理对骨关节炎患者膝关节功能及生活质量的影响

Effects of sodium hyaluronate intraarticular injection with continuing rehabilitation nursing on knee function and quality of life in osteoarthritis patients.

作者信息

Xiao Yong, Du Honghong, Tian Qian, Meng Qingfang

机构信息

Department of Comprehensive Treatment, Qingdao Special Servicemen Recuperation Center of PLA Navy Qingdao 266000, Shandong, China.

Department of Orthopedic and Joint Rehabilitation, Qingdao Special Servicemen Recuperation Center of PLA Navy Qingdao 266000, Shandong, China.

出版信息

Am J Transl Res. 2024 Nov 15;16(11):6573-6580. doi: 10.62347/QHFG7980. eCollection 2024.

DOI:10.62347/QHFG7980
PMID:39678545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11645563/
Abstract

OBJECTIVE

To evaluate the impact of sodium hyaluronate (SH) intraarticular injections plus continuing rehabilitation nursing on knee function and quality of life (QoL) in osteoarthritis (OA) patients.

METHODS

A total of 127 OA patients admitted between May 2021 and May 2023 were selected. The control group (60 cases) received SH intraarticular injections and routine care, while the observation group (67 cases) received SH intraarticular injections plus continuing rehabilitation nursing intervention. Comparative analyses were conducted on treatment efficacy, pain level (Visual Analog Scale (VAS)), negative emotions (Self-rating Anxiety/Depression Scale (SAS/SDS)), knee function (Lysholm Score and Lequesne Index), and QoL (World Health Organization Quality of Life Scale (WHOQOL-100)).

RESULTS

The observation group showed a significantly higher overall treatment efficiency and evident declines in VAS, SAS, and SDS scores compared to the control group (all P<0.05). Additionally, the Lysholm and WHOQOL-100 scores were more significantly elevated than those in the control group (all P<0.05).

CONCLUSIONS

SH intraarticular injections plus continuing rehabilitation nursing can significantly improve knee function and QoL in OA patients.

摘要

目的

评估透明质酸钠（SH）关节腔内注射联合持续康复护理对骨关节炎（OA）患者膝关节功能和生活质量（QoL）的影响。

方法

选取2021年5月至2023年5月期间收治的127例OA患者。对照组（60例）接受SH关节腔内注射及常规护理，观察组（67例）接受SH关节腔内注射联合持续康复护理干预。对治疗效果、疼痛程度（视觉模拟评分法（VAS））、负面情绪（自评焦虑/抑郁量表（SAS/SDS））、膝关节功能（Lysholm评分和Lequesne指数）及生活质量（世界卫生组织生活质量量表（WHOQOL-100））进行比较分析。

结果

与对照组相比，观察组的总体治疗有效率显著更高，VAS、SAS和SDS评分明显下降（均P<0.05）。此外，Lysholm评分和WHOQOL-100评分比对照组升高更显著（均P<0.05）。

结论

SH关节腔内注射联合持续康复护理可显著改善OA患者的膝关节功能和生活质量。

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