Dubois Abigail, Sergio Jordan, Mozdbar Sima, Price Ashley, Stradtman Megan, Thompson Louisa I, Snyder Peter J, Alber Jessica
Interdisciplinary Neuroscience Program, University of Rhode Island, Kingston, RI, United States.
Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, RI, United States.
Front Aging Neurosci. 2024 Nov 29;16:1465812. doi: 10.3389/fnagi.2024.1465812. eCollection 2024.
Subjective visual impairment (VI) is related to cognition in cognitively unimpaired (CU) older adults, mild cognitive impairment (MCI) patients, and Alzheimer's disease (AD) patients. The utility of subjective VI as an indicator for domain-specific cognitive impairment is unknown.
We used the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25 item) and a neuropsychological battery to assess the relationship between subjective VI and domain-specific cognitive performance in CU older adults ( = 58) and MCI patients ( = 16).
The CU group showed a positive relationship between subjective VI and visuospatial performance. CU older adults at high risk for AD demonstrated a unique relationship between subjective VI and attention, processing speed, and executive function. Peripheral vision was related to domain-specific performance in the patient group.
Subjective VI complaints may indicate potential for domain-specific cognitive decline in visuospatial performance, executive function, processing speed, and attention in older adults.
主观视觉障碍（VI）与认知功能未受损（CU）的老年人、轻度认知障碍（MCI）患者及阿尔茨海默病（AD）患者的认知功能有关。主观VI作为特定领域认知障碍指标的效用尚不清楚。
我们使用美国国立眼科研究所视觉功能问卷（NEI-VFQ-25项）和一套神经心理测试工具，评估CU老年人（n = 58）和MCI患者（n = 16）主观VI与特定领域认知表现之间的关系。
CU组中，主观VI与视觉空间表现呈正相关。患AD高风险的CU老年人中，主观VI与注意力、处理速度和执行功能之间存在独特的关系。周边视力与患者组的特定领域表现相关。
主观VI主诉可能表明老年人在视觉空间表现、执行功能、处理速度和注意力方面存在特定领域认知衰退的可能性。
