Huchet R
Int Arch Allergy Appl Immunol. 1985;76(2):182-4. doi: 10.1159/000233687.
Trinitrophenylated lipopolysaccharide (TNP-LPS) at high doses (30 micrograms) induces thymus-independent IgM and IgG anti-TNP responses. At low doses (0.3 microgram) it elicits only an IgM anti-TNP response. TNP-LPS primes for a secondary response of IgG type only when given at high doses (30 micrograms): this response is thymus dependent.
高剂量(30微克)的三硝基苯基化脂多糖(TNP-LPS)可诱导非胸腺依赖性IgM和IgG抗TNP反应。低剂量(0.3微克)时,它仅引发IgM抗TNP反应。只有在高剂量(30微克)给予时,TNP-LPS才引发仅IgG型的二次反应:这种反应是胸腺依赖性的。