Phenalenones and Polyesters from and Structure Revision of Talaromycesone A.

Investigation of the secondary metabolites of the filamentous fungus led to the isolation of two new phenalenone dimers, talarohemiketal A () and talaroazasone A (), and one new macrolide polyester, talaromacrolactone A (), along with the reported oxyphenalenone dimers talaromycesone A (), bacillisporin A (), bacillisporin B (), bacillisporin C (), -bacillisporin F (), and bacillisporin J (), the phenalenone monomer funalenone (), the polyesters 15G256α () and 15G256ν (), and 6-hydroxymellein (). Detailed analysis of 2D NMR correlations, supported by TDDFT calculations, led to the structural revision of talaromycesone A as from previously reported structure . In addition, the previously misassigned NMR spectra of compound have been corrected.