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巨大的基于颅骨骨内和硬脑膜的甲状腺滤泡癌转移瘤:病例说明

A gigantic intraosseous and dural-based calvarial metastatic follicular thyroid carcinoma: illustrative case.

作者信息

Lee Anthony T, Raygor Kunal P, Nichols Noah M, Tarapore Phiroz E

机构信息

Department of Neurological Surgery, University of California, San Francisco, San Francisco, California.

Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee.

出版信息

J Neurosurg Case Lessons. 2024 Dec 16;8(25). doi: 10.3171/CASE24550.

DOI:10.3171/CASE24550
PMID:39680909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11665148/
Abstract

BACKGROUND

Metastatic follicular thyroid carcinoma to the central nervous system (CNS), including the skull and dura, is exceedingly rare.

OBSERVATIONS

The authors present the case of a gigantic, intraosseous, dural-based follicular thyroid carcinoma, highlighting the operative strategy for this mass. They also provide a literature review of CNS metastases of differentiated thyroid carcinoma.

LESSONS

Although follicular thyroid carcinoma rarely metastasizes to the CNS, it should be included in the differential diagnosis of hypervascular intraosseous skull lesions, even in the absence of disseminated metastatic disease. The authors illustrate key operative steps in managing the tumor's hypervascularity, extracranial extension, and posterior sagittal sinus invasion, as well as unintended sequelae from ligating the seemingly occluded anterior and middle third of the superior sagittal sinus in large tumors. https://thejns.org/doi/10.3171/CASE24550.

摘要

背景

转移性滤泡状甲状腺癌累及中枢神经系统(CNS),包括颅骨和硬脑膜,极为罕见。

观察结果

作者报告了一例巨大的、位于骨内、起源于硬脑膜的滤泡状甲状腺癌病例,重点介绍了针对该肿物的手术策略。他们还对分化型甲状腺癌的中枢神经系统转移进行了文献综述。

经验教训

尽管滤泡状甲状腺癌很少转移至中枢神经系统,但即使在无播散性转移疾病的情况下,它也应纳入高血供骨内颅骨病变的鉴别诊断中。作者阐述了处理肿瘤高血供、颅外扩展及后矢状窦侵犯的关键手术步骤,以及在大型肿瘤中结扎看似闭塞的上矢状窦前三分之二时出现的意外后遗症。https://thejns.org/doi/10.3171/CASE24550

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/cdc583113964/CASE24550_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/e39226b63ee9/CASE24550_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/a0576a7edfc0/CASE24550_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/2e3fde29170a/CASE24550_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/cdc583113964/CASE24550_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/e39226b63ee9/CASE24550_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/a0576a7edfc0/CASE24550_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/2e3fde29170a/CASE24550_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c69/11665148/cdc583113964/CASE24550_figure_4.jpg

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本文引用的文献

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Unusual metastases from differentiated thyroid carcinoma: analysis of 36 cases.分化型甲状腺癌的不常见转移:36 例分析。
Endocrine. 2019 Sep;65(3):630-636. doi: 10.1007/s12020-019-01991-0. Epub 2019 Jul 20.
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Outcomes and prognostic factors in thyroid cancer patients with cranial metastases: A retrospective cohort study of 4,683 patients.甲状腺癌颅转移患者的预后和影响因素:4683 例患者的回顾性队列研究。
Int J Surg. 2018 Jul;55:182-187. doi: 10.1016/j.ijsu.2018.06.001. Epub 2018 Jun 5.
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Deaths related to differentiated thyroid cancer: a rare but real event.
与分化型甲状腺癌相关的死亡:一种罕见但真实存在的情况。
Arch Endocrinol Metab. 2017 May-Jun;61(3):222-227. doi: 10.1590/2359-3997000000261. Epub 2017 Mar 27.
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Clinical characteristics and follow-up of intracranial metastases from thyroid cancer.甲状腺癌颅内转移的临床特征及随访
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Rare metastases of well-differentiated thyroid cancers: a systematic review.高分化甲状腺癌的罕见转移:一项系统综述
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Brain metastases from thyroid carcinoma: a retrospective study of 21 patients.甲状腺癌脑转移:21 例回顾性研究。
Thyroid. 2014 Feb;24(2):270-6. doi: 10.1089/thy.2013.0061. Epub 2013 Sep 11.
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Unusual CNS presentation of thyroid cancer.甲状腺癌不寻常的中枢神经系统表现。
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Differentiated thyroid carcinoma presenting with distant metastasis at initial diagnosis clinical outcomes and prognostic factors.分化型甲状腺癌初诊时伴远处转移的临床结局和预后因素。
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Metastatic differentiated thyroid carcinoma: clinical management and outcome of disease in patients with initial and late distant metastases.转移性分化型甲状腺癌:初发和晚期远处转移患者的临床管理及疾病转归
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Clinical management and outcome of papillary and follicular (differentiated) thyroid cancer presenting with distant metastasis at diagnosis.诊断时伴有远处转移的乳头状和滤泡状(分化型)甲状腺癌的临床管理与预后
Cancer. 2007 Oct 1;110(7):1451-6. doi: 10.1002/cncr.22956.