Prott L S, Klein P, Spitznagel F A, Blatz M B, Pieralli S, Gierthmuehlen P C
Department of Prosthodontics, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Department of Preventive and Restorative Sciences, Penn Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
J Esthet Restor Dent. 2025 Mar;37(3):642-663. doi: 10.1111/jerd.13387. Epub 2024 Dec 16.
To investigate the nature and availability of evidence on the clinical performance of posterior partial coverage restorations (PCR) fabricated from different ceramic materials, outcome definitions, measurement methods, study drop-outs and follow ups.
A systematic literature search (inception-February 2024) was performed through MEDLINE, Scopus, CENTRAL, ClinicalTrials.gov, and the International Clinical Trials Registry Platform to identify clinical studies with a focus on posterior PCRs (onlays, occlusal veneers and partial crowns) with a minimum follow-up of 1 year. Thirteen of 31 included studies were randomized controlled trials (RCT) and 18 non-randomized studies of intervention (NRS). Six RCTs compared two different ceramic materials and might be suitable for meta-analysis. Differences in study design, definition of survival, evaluation methods, and statistical models for survival analysis were identified as reasons for expected heterogeneity among studies. The most common reasons for restoration failures were ceramic fractures and retention loss.
The evidence informing the effect of PCRs varied in definitions of survival and failure, complication classifications, and workflow approaches. RCTs addressing clinical performance of PCRs comparing different ceramic materials are available for conducting systematic reviews and meta-analyses.
探讨不同陶瓷材料制成的后牙部分覆盖修复体(PCR)的临床性能、结果定义、测量方法、研究失访和随访方面的证据性质及可得性。
通过MEDLINE、Scopus、CENTRAL、ClinicalTrials.gov和国际临床试验注册平台进行了系统的文献检索(起始时间-2024年2月),以识别重点关注后牙PCR(高嵌体、咬合贴面和部分冠)且随访至少1年的临床研究。纳入的31项研究中有13项为随机对照试验(RCT),18项为非随机干预研究(NRS)。6项RCT比较了两种不同的陶瓷材料,可能适用于荟萃分析。研究设计、生存定义、评估方法和生存分析统计模型的差异被确定为研究间预期异质性的原因。修复失败的最常见原因是陶瓷材料断裂和固位丧失。
关于PCR效果的证据在生存和失败的定义、并发症分类以及工作流程方法方面存在差异。有针对比较不同陶瓷材料的PCR临床性能的RCT,可用于进行系统评价和荟萃分析。