Bousquet J, Dhivert H, Clauzel A M, Hewitt B, Michel F B
J Allergy Clin Immunol. 1985 Jan;75(1 Pt 1):70-4. doi: 10.1016/0091-6749(85)90015-6.
Although the sunflower belongs to the Compositeae family, allergy to sunflower pollen is not common. The occurrence of occupational allergy to this pollen species made it possible to characterize cross-reactive patterns of Compositeae pollens in a human experimental model. A 24-yr-old man developed rhinitis and conjunctivitis over 5 yr of exposure to sunflower pollens, and asthma developed during the fifth year. All respiratory and occular symptoms disappeared after he was removed from exposure, but he had a food allergic reaction while he was eating honey containing 30% sunflower pollens. The diagnosis of occupational allergy was based on history, skin prick tests and RAST to the pollen. Bronchial provocation tests performed after removal from exposure confirmed the sensitivity to sunflower pollens but there was no nonspecific hyperreactivity. It was found by RAST inhibition that sunflower pollen does not cross-react with other Compositeae pollens tested or with sunflower seed. The honey that elicited food intolerance was demonstrated to inhibit significantly sunflower pollen RAST.
尽管向日葵属于菊科植物，但对向日葵花粉过敏并不常见。对这种花粉的职业性过敏的发生使得在人体实验模型中表征菊科花粉的交叉反应模式成为可能。一名24岁的男子在接触向日葵花粉5年期间出现了鼻炎和结膜炎，并在第5年患上了哮喘。在他停止接触后，所有呼吸道和眼部症状都消失了，但他在食用含有30%向日葵花粉的蜂蜜时出现了食物过敏反应。职业性过敏的诊断基于病史、皮肤点刺试验和针对该花粉的放射性变应原吸附试验（RAST）。停止接触后进行的支气管激发试验证实了对向日葵花粉的敏感性，但没有非特异性高反应性。通过RAST抑制发现，向日葵花粉与测试的其他菊科花粉或向日葵种子没有交叉反应。引发食物不耐受的蜂蜜被证明能显著抑制向日葵花粉RAST。
