文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

有序介孔二氧化硅材料在药物递送中的应用：综述

Application of Ordered Porous Silica Materials in Drug Delivery: A Review.

作者信息

Liu Wenwen, Wu Junlin, Jiang Zehao, Zhang Xinyu, Wang Zhenxiang, Meng Fanjun, Liu Zidi, Zhang Teng

机构信息

Nanjing University of Science and Technology Hospital, Nanjing University of Science and Technology, Nanjing 210094, China.

School of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China.

出版信息

Molecules. 2024 Dec 3;29(23):5713. doi: 10.3390/molecules29235713.

DOI:10.3390/molecules29235713
PMID:39683872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11643771/
Abstract

Nanotechnology has significantly advanced various fields, including therapeutic delivery, through the use of nanomaterials as drug carriers. The biocompatibility of ordered porous silica materials makes them promising candidates for drug delivery systems, particularly in the treatment of cancer and other diseases. This review summarizes the use of microporous zeolites and mesoporous silica materials in drug delivery, focusing on their physicochemical properties and applications as drug carriers. Special emphasis is placed on strategies for encapsulation and functionalization, highlighting their role in enhancing drug loading and enabling targeted delivery. In conclusion, while ordered porous silica materials hold great potential for drug delivery systems, certain challenges remain.

摘要

纳米技术通过使用纳米材料作为药物载体，在包括治疗递送在内的各个领域都取得了显著进展。有序多孔二氧化硅材料的生物相容性使其成为药物递送系统的有前途的候选材料，特别是在癌症和其他疾病的治疗中。本综述总结了微孔沸石和介孔二氧化硅材料在药物递送中的应用，重点关注它们作为药物载体的物理化学性质和应用。特别强调了封装和功能化策略，突出了它们在提高药物负载量和实现靶向递送方面的作用。总之，虽然有序多孔二氧化硅材料在药物递送系统中具有巨大潜力，但仍存在一些挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/4528515c23ad/molecules-29-05713-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/635485b5edd8/molecules-29-05713-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/e8d97cf2949e/molecules-29-05713-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/9ba1c9382608/molecules-29-05713-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/4528515c23ad/molecules-29-05713-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/635485b5edd8/molecules-29-05713-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/e8d97cf2949e/molecules-29-05713-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/9ba1c9382608/molecules-29-05713-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa5/11643771/4528515c23ad/molecules-29-05713-g004.jpg

相似文献

[1]
Application of Ordered Porous Silica Materials in Drug Delivery: A Review.

Molecules. 2024-12-3

[2]
Functionalized mesoporous silica particles for application in drug delivery system.

Mini Rev Med Chem. 2012-7

[3]
Exploring the physicochemical interactions and loading strategies of mesoporous silicon dioxide nanoparticles for drug delivery.

Eur J Pharm Biopharm. 2025-3

[4]
Ordered Mesoporous Silica Delivering siRNA as Cancer Nanotherapeutics: A Comprehensive Review.

ACS Biomater Sci Eng. 2024-5-13

[5]
Controlled drug delivery systems for cancer based on mesoporous silica nanoparticles.

Int J Nanomedicine. 2019-5-8

[6]
Facile Synthesis of Three Types of Mesoporous Silica Microspheres as Drug Delivery Carriers and their Sustained-Release Properties.

Curr Drug Deliv. 2023

[7]
Drastic sensitivity enhancement in 29Si MAS NMR of zeolites and mesoporous silica materials by paramagnetic doping of Cu2+.

Phys Chem Chem Phys. 2013-8-28

[8]
Single Crystal FLIM Characterization of Clofazimine Loaded in Silica-Based Mesoporous Materials and Zeolites.

Int J Mol Sci. 2019-6-12

[9]
Recent advances in porous nanoparticles for drug delivery in antitumoral applications: inorganic nanoparticles and nanoscale metal-organic frameworks.

Expert Opin Drug Deliv. 2017-6

[10]
Silica materials in drug delivery applications.

Curr Drug Discov Technol. 2011-9

引用本文的文献

[1]
Quercetin loaded-magnetic zeolite nano-composite material and evaluate its anti-cancer effect.

Naunyn Schmiedebergs Arch Pharmacol. 2025-4-14

[2]
Modified diatom-based ocular suspension for sustained diclofenac sodium delivery: a novel drug carrier approach.

BMC Pharmacol Toxicol. 2025-4-9

本文引用的文献

[1]
Evaluation of Zeolite Composites by IR and NMR Spectroscopy.

Molecules. 2024-9-19

[2]
Targeted Drug Delivery Strategies for the Treatment of Hepatocellular Carcinoma.

Molecules. 2024-9-16

[3]
Rice Husk as Raw Material in Synthesis of NaA (LTA) Zeolite.

Molecules. 2024-9-16

[4]
Recent Advances in Drug Delivery Strategies for High-Risk BCG-Unresponsive Non-Muscle Invasive Bladder Cancer: A Brief Review from 2018 to 2024.

Pharmaceutics. 2024-8-30

[5]
Drug Delivery Systems for Glaucoma: A Narrative Review.

Pharmaceuticals (Basel). 2024-9-2

[6]
Zeolite-based nanoparticles drug delivery systems in modern pharmaceutical research and environmental remediation.

Heliyon. 2024-8-16

[7]
Polyphenol-stabilized coacervates for enzyme-triggered drug delivery.

Nat Commun. 2024-8-24

[8]
Application of South African heulandite (HEU) zeolite for the adsorption and removal of Pb and Cd ions from aqueous water solution: Experimental and computational study.

Heliyon. 2024-7-15

[9]
Theranostics Using MCM-41-Based Mesoporous Silica Nanoparticles: Integrating Magnetic Resonance Imaging and Novel Chemotherapy for Breast Cancer Treatment.

Int J Mol Sci. 2024-7-25

[10]
Regulating Drug Release Performance of Acid-Triggered Dimeric Prodrug-Based Drug Self-Delivery System by Altering Its Aggregation Structure.

Molecules. 2024-7-31

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索