Nakada Tsubasa, Kurotani Kayo, Kozawa Takako, Seino Satoshi, Murota Shinichi, Eto Miki, Shimasawa Junko, Shimizu Yumiko, Tsurugano Shinobu, Katsukawa Fuminori, Sakamoto Kazunori, Washizaki Hironori, Ishigaki Yo, Sakamoto Maki, Takadama Keiki, Yanai Keiji, Matsuo Osamu, Kameue Chiyoko, Suzuki Hitomi, Ohkawara Kazunori
Graduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo 182-8585, Japan.
Graduate School of Life Sciences, Showa Women's University, Tokyo 154-8533, Japan.
Healthcare (Basel). 2024 Nov 26;12(23):2365. doi: 10.3390/healthcare12232365.
Frailty is a growing public health challenge in Japan's rapidly aging population, where 28.8% are aged ≥ 65. While multicomponent interventions have shown potential in preventing frailty, traditional face-to-face programs face accessibility challenges. This study evaluated the feasibility and short-term changes of an online multicomponent intervention on frailty-related factors among community-dwelling older adults. In this single-arm feasibility study, 132 participants (mean age 75.7; standard deviation 4.8 years, 65.2% women) completed a six-week online intervention combining exercise, nutrition education, cognitive activities, and the Coimagination Method to foster social connections, meeting weekly for 75 min sessions in groups of up to 10 participants. The intervention demonstrated feasibility with a 96.4% retention rate and a 94.0% average participation rate. While no significant changes were observed in physical activity levels, autonomic nervous system indicators, or cognitive function, carotenoid scores and hemoglobin concentration improved significantly, with more pronounced improvements among women than men. This study demonstrates the high feasibility of online multicomponent interventions for older adults and suggests potential benefits for nutritional status markers, particularly among women. These findings indicate a promising and accessible approach to frailty prevention, though randomized controlled trials with longer intervention periods and direct frailty assessments are required to establish effectiveness conclusively. Study Trial registration: UMIN Clinical Trials Registry (UMIN000053089).
在日本人口迅速老龄化的情况下，衰弱已成为一个日益严峻的公共卫生挑战，该国28.8%的人口年龄在65岁及以上。虽然多组分干预措施在预防衰弱方面已显示出潜力，但传统的面对面项目面临可及性挑战。本研究评估了一项在线多组分干预措施对社区居住老年人衰弱相关因素的可行性和短期变化。在这项单臂可行性研究中，132名参与者（平均年龄75.7岁；标准差4.8岁，65.2%为女性）完成了一项为期六周的在线干预，该干预结合了运动、营养教育、认知活动以及促进社会联系的共同想象方法，参与者以每组最多10人的形式每周进行75分钟的小组会议。该干预措施显示出可行性，保留率为96.4%，平均参与率为94.0%。虽然在身体活动水平、自主神经系统指标或认知功能方面未观察到显著变化，但类胡萝卜素得分和血红蛋白浓度显著改善，女性的改善比男性更明显。本研究证明了在线多组分干预措施对老年人具有高度可行性，并表明对营养状况指标有潜在益处，尤其是在女性中。这些发现表明了一种有前景且可及的预防衰弱方法，不过需要进行干预期更长且有直接衰弱评估的随机对照试验来最终确定其有效性。研究试验注册：UMIN临床试验注册中心（UMIN000053089）。
