Shafiroff B B, Nightingale G, Baxter T J, O'Brien B M
Ann Plast Surg. 1979 Sep;3(3):199-210. doi: 10.1097/00000637-197909000-00002.
Lymphaticovenous anastomosis has proved valuable in the treatment of obstructive lymphedema. Histological studies of this anastomosis have shown the lymphatic component to be almost inactive in anastomotic healing. In order to clarify the role of the lymphatics, experimental lymphaticolymphatic anastomoses were performed in canine femoral lymphatics. The technique developed calls for eight to ten 19 mu sutures to prevent vessel wall collapse, and preservation of the vasa vasorum. Vessels were harvested from one hour to six weeks after anastomosis. Scanning electron microscopy and conventional light histology revealed the lymphatics to have active healing of the intima with complete reendothelialization by two weeks. The techniques developed in this study are directly applicable to human lymphaticovenous anastomosis.
淋巴管静脉吻合术已被证明在阻塞性淋巴水肿的治疗中具有重要价值。对这种吻合术的组织学研究表明，淋巴管成分在吻合口愈合过程中几乎没有活性。为了阐明淋巴管的作用，在犬股淋巴管中进行了实验性淋巴管-淋巴管吻合术。所开发的技术需要使用8至10根19微米的缝线来防止血管壁塌陷，并保留血管滋养管。在吻合术后1小时至6周采集血管。扫描电子显微镜和传统光学组织学显示，淋巴管内膜在两周内具有活跃的愈合过程，内皮细胞完全重新形成。本研究中开发的技术可直接应用于人体淋巴管静脉吻合术。
