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使用新型预测量腱索环简化二尖瓣修复术

Simplifying Mitral Valve Repair with Novel Premeasured Chordal Loops.

作者信息

Shell Daniel, Bunwatcharaphan Natcha, Seitz Michael, Rowland Michael, Chengalath Manoras, Yap Cheng-Hon

机构信息

Department of Cardiothoracic Surgery, Barwon Health, Geelong, VIC 3220, Australia.

School of Medicine, Deakin University, Geelong, VIC 3216, Australia.

出版信息

J Clin Med. 2024 Nov 21;13(23):7029. doi: 10.3390/jcm13237029.

Abstract

The "respect" approach to surgical mitral valve repair, which involves implanting artificial neochordae, is gaining increased adoption. Surgeons are possibly prone to error in the manual construction of neochordae, which can lead to prolonged cross-clamp times. Novel systems such as Chord-X Pre-Measured Loops (On-X Life Technologies, Inc., Austin, TX, USA) eliminate the need for manual neochordae construction, potentially simplifying the mitral repair procedure. However, clinical data on its use are currently limited to a small publication. : We conducted a retrospective cohort study to evaluate the use of Chord-X loops in 40 consecutive patients who underwent surgery in Geelong, Victoria, Australia, between May 2020 and February 2024. Three surgeons participated in this study. : All patients were referred for severe mitral valve regurgitation secondary to myxomatous degeneration, with P2 prolapse being the most common pathology. Chord-X Pre-Measured Loops effectively corrected a variety of leaflet pathologies, including bi-leaflet disease, with a single set of loops sufficing in most patients. Intraoperative and follow-up echocardiographic assessments revealed no greater than mild mitral regurgitation in any patient, with 75% exhibiting no or trace mitral regurgitation. : The Chord-X Pre-Measured Loops system demonstrated safety, efficacy, and reproducibility across all patients. Surgeons were able to easily adopt this technology without requiring additional training. We believe this technology offers a safe option for surgeons performing low-volume mitral repair surgeries.

摘要

涉及植入人工新腱索的二尖瓣手术修复“尊重”法越来越受到广泛应用。外科医生在手工构建新腱索时可能容易出错,这可能导致体外循环时间延长。诸如Chord-X预测量环(On-X Life Technologies公司,美国德克萨斯州奥斯汀)等新型系统消除了手工构建新腱索的需求,可能简化二尖瓣修复手术。然而,目前关于其使用的临床数据仅限于一篇小论文。我们进行了一项回顾性队列研究,以评估2020年5月至2024年2月期间在澳大利亚维多利亚州吉朗接受手术的40例连续患者中Chord-X环的使用情况。三位外科医生参与了这项研究。所有患者均因黏液瘤样变性继发严重二尖瓣反流而就诊,P2脱垂是最常见的病理情况。Chord-X预测量环有效地纠正了各种瓣叶病变,包括双瓣叶疾病,大多数患者使用一套环就足够了。术中及随访超声心动图评估显示,所有患者的二尖瓣反流均不超过轻度,75%的患者无或仅有微量二尖瓣反流。Chord-X预测量环系统在所有患者中均显示出安全性、有效性和可重复性。外科医生能够轻松采用这项技术,无需额外培训。我们认为,这项技术为进行低容量二尖瓣修复手术的外科医生提供了一种安全的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9214/11642386/5e1f0a78cfb8/jcm-13-07029-g001.jpg

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