Ishimoto Ryu, Mutsuzaki Hirotaka, Shimizu Yukiyo, Takeuchi Ryoko, Matsumoto Shuji, Hada Yasushi
Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba 305-8575, Japan.
Department of Rehabilitation Medicine, Ibaraki Prefectural University of Health Sciences Hospital, Ami 300-0331, Japan.
J Clin Med. 2024 Nov 22;13(23):7071. doi: 10.3390/jcm13237071.
: Sarcopenic obesity adversely affects physical function and activities of daily living (ADL) in older individuals and patients undergoing rehabilitation. This condition is also common in individuals with spinal cord injury (SCI); however, its relationship with ADL in this group remains unclear. Hence, this study examined the association between sarcopenic obesity and ADL in individuals with SCI. : This retrospective cross-sectional study identified sarcopenia using the low skeletal muscle mass index (SMI) and Asian Working Group for Sarcopenia reference values. Obesity was defined as a body fat percentage (%BF) exceeding 25% in men and 35% in women. Sarcopenic obesity was identified when both the sarcopenia and obesity criteria were met. The primary outcome, ADL, was measured using the Functional Independence Measure (FIM). Multiple linear regression models were used to analyze the associations among the SMI, %BF, and FIM scores, after adjusting for age, sex, lesion level, injury severity, comorbidities, and injury duration. : Of 82 participants (median age: 63.5 years; 18.3% women), 62.2% had sarcopenic obesity. Participants with sarcopenic obesity (54 vs. 69 points, = 0.006) had significantly lower FIM motor scores than those without this condition. Multiple linear regression analysis revealed that SMI (β = 0.416, < 0.001) and %BF (β = -0.325, = 0.009) were independently associated with the FIM motor scores. : Decreased SMI and increased %BF in patients with SCI were independently associated with decreased ADL independence. Routine body composition assessments are necessary for early detection and intervention in this population.
肌肉减少性肥胖对老年人和正在接受康复治疗的患者的身体功能及日常生活活动(ADL)有不利影响。这种情况在脊髓损伤(SCI)患者中也很常见;然而,其与该群体ADL的关系仍不明确。因此,本研究调查了SCI患者中肌肉减少性肥胖与ADL之间的关联。 :这项回顾性横断面研究使用低骨骼肌质量指数(SMI)和亚洲肌肉减少症工作组的参考值来确定肌肉减少症。肥胖定义为男性体脂百分比(%BF)超过25%,女性超过35%。当同时满足肌肉减少症和肥胖标准时,确定为肌肉减少性肥胖。主要结局指标ADL使用功能独立性测量(FIM)进行评估。在调整年龄、性别、损伤水平、损伤严重程度、合并症和损伤持续时间后,使用多元线性回归模型分析SMI、%BF和FIM评分之间的关联。 :在82名参与者(中位年龄:63.5岁;18.3%为女性)中,62.2%患有肌肉减少性肥胖。患有肌肉减少性肥胖的参与者(54分对69分,P = 0.006)的FIM运动评分显著低于无此情况的参与者。多元线性回归分析显示,SMI(β = 0.416,P < 0.001)和%BF(β = -0.325,P = 0.009)与FIM运动评分独立相关。 :SCI患者中SMI降低和%BF升高与ADL独立性降低独立相关。对该人群进行常规身体成分评估对于早期发现和干预是必要的。